Recombinant Human Anti-GPCR Antibody
CAT#: MHH-414
Recombinant Human Antibody specifically binds to GPCR, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-GPCR mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-GPCR mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Gene Expression
Normal Tissue
Figure 1 Colon
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62890/141594_A_8_3.jpg
Normal Tissue
Figure 2 Liver
Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62890/141594_A_8_4.jpg
Normal Tissue
Figure 3 Placenta
Trophoblastic cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62890/141594_A_3_7.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (ASC diff, HHSteC, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000179921-GPBAR1
❮
❯
Specifications
- Immunogen
- G protein-coupled receptor
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native G protein-coupled receptor
- Applications
- Used for immunoassaytechniques such as: Western blot; Enzyme-linked Immunosorbent Assay; Immunohistochemistry; Functional Study
Product Property
- Purity
- Purity>95% by SDS-PAGE
- Storage
- Store at -20°C. Avoid multiple freeze/thaw cycles.
Target
- Alternative Names
- G protein–coupled receptors; GPCRs; seven-transmembrane domain receptors; 7TM receptors; heptahelical receptors; serpentine receptor; G protein–linked receptors; GPLR; G protein-coupled receptor; GPCR
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Related Signaling Pathways
cAMP Signaling Pathway
MAPK Signaling Pathway
PPAR Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "GPCR"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-414 | Recombinant Anti-GPCR Antibody | WB, ELISA, IHC, FuncS | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-414-F(E) | Recombinant Anti-GPCR Antibody Fab Fragment | ELISA, RIA, FuncS | Fab |
| MHH-414-F(E) | Recombinant Human Anti-GPCR Antibody Fab Fragment | WB, Dot, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-414-S(P) | Recombinant Anti-GPCR Antibody scFv Fragment | FC, WB, FuncS | scFv |
| MHH-414-S(P) | Recombinant Human Anti-GPCR Antibody scFv Fragment | IF, Neut, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-070 | Recombinant Anti-Human GPCRs VHH Single Domain Antibody | IHC, FC, CA, FuncS | Llama VHH |
| HPAB-1134-CN-VHH | Camelid Anti-GPCR Recombinant Antibody (HPAB-1134-CN-VHH) | WB | Camelid VHH |
| HPAB-1135-CN-VHH | Camelid Anti-GPCR Recombinant Antibody (HPAB-1135-CN-VHH) | WB | Camelid VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-388CQ | Human Anti-GPCR Recombinant Antibody (TAB-388CQ) | ELISA | Human IgG |
| TAB-388CQ-S(P) | Human Anti-GPCR Recombinant Antibody; scFv Fragment (TAB-388CQ-S(P)) | ELISA | Human scFv |
| TAB-388CQ-F(E) | Human Anti-GPCR Recombinant Antibody; Fab Fragment (TAB-388CQ-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-065 | Recombinant Mouse Anti-GPCR Antibody | WB, Neut, FuncS | IgG |
| PABX-065-S (P) | Recombinant Mouse Anti-GPCR Antibody scFv Fragment | WB, Neut, FuncS | scFv |
| PABX-065-F (E) | Recombinant Mouse Anti-GPCR Antibody Fab Fragment | WB, Neut, FuncS | Fab |
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