Recombinant Human Anti-human GDF15 Antibody (CAT#: MHH-391)
Recombinant Human Antibody specifically binds to Human GDF15, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-GDF15 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-GDF15 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11191/1404_F3_1_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11191/1404_F3_1_selected.jpg
Figure 2 Placenta
(Cytotrophoblasts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Syncytiotrophoblasts - cell body
Staining: High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining: High
Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11191/27866_A_1_7.jpg
(Cytotrophoblasts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Syncytiotrophoblasts - cell body
Staining: High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining: High
Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11191/27866_A_1_7.jpg
Figure 3 RNA cell line category: Cell line enhanced (BEWO, Hep G2, HHSteC, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130513-GDF15
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130513-GDF15
Specifications
- Immunogen
- Human growth differentiation factor 15
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human growth differentiation factor 15
- Species Reactivity
- Human
- Applications
- Products can be used for: Enzyme-linked Immunosorbent Assay; Western blot; Functional Study
Product Property
- Purity
- 90–95% (SDS-PAGE)
- Storage
- ≤6 months at 4°C; ≥6 months at -20°C.
Target
- Alternative Names
- GDF15; growth differentiation factor 15; PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15; growth/differentiation factor 15; NRG-1; PTGF-beta; placental TGF-beta; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; prostate differentiation factor;
- Gene ID
- 9518
- UniProt ID
- Q99988
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-391 | Recombinant Anti-human GDF15 Antibody | ELISA, WB, IF, FuncS | IgG |
| MOB-0141CT | Recombinant Mouse anti-Human GDF15 Monoclonal antibody (NN0408-20B4) | FC, WB | |
| HPAB-0334-CN | Mouse Anti-GDF15 Recombinant Antibody (HPAB-0334-CN) | ELISA, WB | Mouse IgG1, κ |
| HPAB-0142-YJ | Human Anti-GDF15 Recombinant Antibody (HPAB-0142-YJ) | Inhib, FuncS | Chimeric (mouse/human) IgG1, κ |
| HPAB-0143-YJ | Human Anti-GDF15 Recombinant Antibody (HPAB-0143-YJ) | Inhib, FuncS | Humanized IgG1, κ |
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