A*02:01/Human EZH2 (YMCSFLFNL) MHC Monomer
CAT#: MHC-YF275
This product is a MHC monomer of biotinylated peptide/MHC complex composed EZH2-derived peptide of YMCSFLFNL sequence covering 666-674 and A*02:01 molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SiHa
Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29131/2008_C2_16_cr5f1a9e9d6c53d_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9589/if_selected.jpg
Subcellular Location
Figure 3 IF staining of human cell line REH
Immunofluorescent staining of human cell line REH shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29131/2027_D2_1_red_green.jpg
Subcellular Location
Figure 4 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29131/582_H8_1_red_green.jpg
Normal Tissue
Figure 5 Colon
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9589/23664_A_9_3.jpg
Normal Tissue
Figure 6 Testis
Elongated or late spermatids
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Pachytene spermatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Preleptotene spermatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Round or early spermatids
Staining: High
Intensity: Strong
Quantity:>75%
Spermatogonia cells
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9589/23664_A_6_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9589/23664_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000106462-EZH2
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Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- EZH2
- Antigen Species
- Human
- Peptide
- YMCSFLFNL
- Range
- 666-674
- Conjugate
- Biotin
- Application
- MHC Multimer
Target
- Antigen Introduction
- This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.
- Alternative Names
- EZH2; enhancer of zeste 2 polycomb repressive complex 2 subunit; WVS; ENX1; EZH1; KMT6; WVS2; ENX-1
- Gene ID
- 2146
- UniProt ID
- Q15910
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC078 | PE-A*02:01/Human EZH2 (YMCSFLFNL) MHC Tetramer | FCM | |
| MHC-CN0657 | PE-A*02:01/Human EZH2 (SQADALKYV) MHC Tetramer | FCM, IHC | |
| MHC-CN0658 | APC-A*02:01/Human EZH2 (SQADALKYV) MHC Tetramer | FCM, IHC | |
| MHC-CN0659 | FITC-A*02:01/Human EZH2 (SQADALKYV) MHC Tetramer | FCM, IHC | |
| MHC-CN0660 | A*02:01/Human EZH2 (SQADALKYV) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1221 | Hi-Affi™ Rabbit Anti-EZH2 Recombinant Antibody (clone DS1221AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0905-CN | Rabbit Anti-EZH2 Recombinant Antibody (clone CBACN-338) | WB, IF, IHC | Rabbit IgG |
| VS3-QX394 | Mouse Anti-EZH2 Recombinant Antibody (clone 3D2A4) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS3-QX395 | Mouse Anti-EZH2 Recombinant Antibody (clone 144CT2.1.1.5) | WB, ICC, IHC | Mouse IgG1, κ |
| VS3-QX396 | Mouse Anti-EZH2 Recombinant Antibody (clone 6F-4G) | WB, IHC, FC | Mouse IgG1 |
| VS3-WK1001 | Rabbit Anti-EZH2 Recombinant Antibody (VS3-WK1001) | WB, ICC, IF, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY197 | Mouse Anti-NHP EZH2 Recombinant Antibody (clone H.547.3) | WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2396 | Anti-EZH2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2397 | Anti-Mouse EZH2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2398 | Anti-Rat EZH2 Immunohistochemistry Kit | IHC |
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