A*03:01/Human MCL1 (RLLFFAPTR) MHC Tetramer
CAT#: MHC-CN1028
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8455/if_selected.jpg
Normal Tissue
Figure 2 Appendix
High expression in appendix
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8455/22739_A_1_2_val_selected.jpg
Normal Tissue
Figure 3 IHC staining of human stomach
Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_3_1_selected.jpg
Normal Tissue
Figure 4 IHC staining of human placenta
Immunohistochemical staining of human placenta shows strong positivity in trophoblastic cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/68195/ihc_selected.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_7_3.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_6_6.jpg
Normal Tissue
Figure 7 Thyroid gland
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_B_3_5.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enriched (U-698)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000143384-MCL1
❮
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Specifications
- Allele
- A*03:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- MCL1
- Antigen Species
- Human
- Peptide
- RLLFFAPTR
- Conjugate
- Unconjugated
- Application
- FCM, IHC
Target
- Antigen Introduction
- This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]
- Alternative Names
- MCL1, BCL2 Family Apoptosis Regulator; Myeloid Cell Leukemia Sequence 1 (BCL2-Related); Bcl-2-Related Protein EAT/Mcl1; Myeloid Cell Leukemia 1; Bcl-2-Like Protein 3; Bcl2-L-3; Mcl1/EAT; BCL2L3; Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1;
- Gene ID
- 4170
- UniProt ID
- Q07820
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Protocol & Troubleshooting
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|---|---|---|---|
| MOB-2309z | Mouse Anti-MCL1 Recombinant Antibody (clone 26F6) | WB, ELISA, IF, IHC | Mouse IgG1 |
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| ZG-0272C | Mouse Anti-MCL1 Recombinant Antibody (ZG-0272C) | WB, IHC, IF, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
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| MOR-2189 | Hi-Affi™ Recombinant Rabbit Anti-MCL1 Monoclonal Antibody (DS2189AB) | ICC, IF, WB, IHC-P, ICC, FC, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN1025 | PE-A*03:01/Human MCL1 (RLLFFAPTR) MHC Tetramer | FCM, IHC | |
| MHC-CN1026 | APC-A*03:01/Human MCL1 (RLLFFAPTR) MHC Tetramer | FCM, IHC | |
| MHC-YF546 | A*01:01/Human MCL-1 (QSLEIISRY) MHC Pentamer | FCM | |
| MHC-YF547 | A*02:01/Human MCL-1 (AVLPLLELV) MHC Pentamer | FCM | |
| MHC-YF548 | A*03:01/Human MCL-1 (RLLFFAPTR) MHC Pentamer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBS-0143 | Human Anti-MCL1 Recombinant Antibody (Clone 01JF43); Fab Fragment | ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBS-0143 | Human Anti-MCL1 Recombinant Antibody (Clone 01JF43); scFv Fragment | ELISA, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1318 | Anti-MCL1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4301 | Anti-Mouse MCL1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4300 | Anti-Human MCL1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4302 | Anti-Rat MCL1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC710 | CytoStream™ Rabbit Anti-MCL1 Recombinant Antibody (VS13-YC710) | WB, ICC, IF, IHC-P, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC402 | Recombinant Anti-MCL1 Vesicular Antibody, EV Displayed (VS-0425-YC402) | ELISA, FC, Cell-uptake |
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