Recombinant Mouse anti-Human MCL1 Monoclonal antibody (49H4) (CAT#: MOB-1225CT)
Recombinant Mouse monoclonal antibody to Human MCL1, expressed in Chinese Hamster Ovary cells(CHO).
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8455/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8455/if_selected.jpg
Figure 2 Appendix
(High expression in appendix)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8455/22739_A_1_2_val_selected.jpg
(High expression in appendix)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8455/22739_A_1_2_val_selected.jpg
Figure 3 IHC staining of human stomach
(Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_3_1_selected.jpg
(Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_3_1_selected.jpg
Figure 4 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows strong positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68195/ihc_selected.jpg
(Immunohistochemical staining of human placenta shows strong positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68195/ihc_selected.jpg
Figure 5 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_7_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_7_3.jpg
Figure 6 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_6_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_6_6.jpg
Figure 7 Thyroid gland
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_B_3_5.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_B_3_5.jpg
Figure 8 RNA cell line category: Cell line enriched (U-698)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000143384-MCL1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000143384-MCL1
Specifications
- Immunogen
- Recombinant fragment corresponding to a 255 amino acid fragment of the N terminal region of human MCL1
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- 49H4
- Applications
- Used for immunoassay techniques such as: Immunohistochemistry paraffin embedded sections
- Conjugate
- Unconjugated
Product Property
- Purity
- Tissue culture supernatant
- Format
- Liquid
- Buffer
- Preservative: 15mM Sodium Azide Constituents: Tissue culture supernatant
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- MCL1; myeloid cell leukemia 1; TM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT; induced myeloid leukemia cell differentiation protein Mcl-1; bcl-2-like protein 3; myeloid cell leukemia ES; bcl-2-related protein EAT/mcl1; myeloid cell leukemia sequence 1 (BCL2-related);
- Gene ID
- 4170
- UniProt ID
- Q07820
- Protein Refseq
- NP_001184249
- Function
- BH3 domain binding; protein binding; protein channel activity; protein heterodimerization activity;
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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|---|---|---|---|
| MOB-2309z | Mouse Anti-MCL1 Recombinant Antibody (clone 26F6) | WB, ELISA, IF, IHC | Mouse IgG1 |
| MRO-0971-CN | Recombinant Rabbit Anti-MCL1 Monoclonal Antibody (CBACN-355) | WB, IF, IHC, IP, FC | Rabbit IgG |
| MRO-2028-CN | Rabbit Anti-MCL1 Polyclonal Antibody (MRO-2028-CN) | IF, IHC | Rabbit IgG |
| ZG-0272C | Mouse Anti-MCL1 Recombinant Antibody (ZG-0272C) | WB, IHC, IF, ELISA | Mouse IgG |
| VS3-FY906 | Recombinant Rabbit Anti-MCL1 Antibody (clone R04-3A4) | WB, ICC, IF, IP | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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