Recombinant Mouse anti-Human MCL1 Monoclonal antibody (49H4)
CAT#: MOB-1225CT
Recombinant Mouse monoclonal antibody to Human MCL1, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8455/if_selected.jpg
Normal Tissue
Figure 2 Appendix
High expression in appendix
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8455/22739_A_1_2_val_selected.jpg
Normal Tissue
Figure 3 IHC staining of human stomach
Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_3_1_selected.jpg
Normal Tissue
Figure 4 IHC staining of human placenta
Immunohistochemical staining of human placenta shows strong positivity in trophoblastic cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/68195/ihc_selected.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_7_3.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_6_6.jpg
Normal Tissue
Figure 7 Thyroid gland
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_B_3_5.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enriched (U-698)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000143384-MCL1
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Specifications
- Immunogen
- Recombinant fragment corresponding to a 255 amino acid fragment of the N terminal region of human MCL1
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- 49H4
- Applications
- Used for immunoassay techniques such as: Immunohistochemistry paraffin embedded sections
- Conjugate
- Unconjugated
Product Property
- Purity
- Tissue culture supernatant
- Format
- Liquid
- Buffer
- Preservative: 15mM Sodium Azide Constituents: Tissue culture supernatant
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- MCL1; myeloid cell leukemia 1; TM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT; induced myeloid leukemia cell differentiation protein Mcl-1; bcl-2-like protein 3; myeloid cell leukemia ES; bcl-2-related protein EAT/mcl1; myeloid cell leukemia sequence 1 (BCL2-related);
- Gene ID
- 4170
- UniProt ID
- Q07820
- Protein Refseq
- NP_001184249
- Function
- BH3 domain binding; protein binding; protein channel activity; protein heterodimerization activity;
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN1025 | PE-A*03:01/Human MCL1 (RLLFFAPTR) MHC Tetramer | FCM, IHC | |
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| MHC-YF546 | A*01:01/Human MCL-1 (QSLEIISRY) MHC Pentamer | FCM | |
| MHC-YF547 | A*02:01/Human MCL-1 (AVLPLLELV) MHC Pentamer | FCM | |
| MHC-YF548 | A*03:01/Human MCL-1 (RLLFFAPTR) MHC Pentamer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBS-0143 | Human Anti-MCL1 Recombinant Antibody (Clone 01JF43); Fab Fragment | ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBS-0143 | Human Anti-MCL1 Recombinant Antibody (Clone 01JF43); scFv Fragment | ELISA, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1318 | Anti-MCL1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4301 | Anti-Mouse MCL1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4300 | Anti-Human MCL1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4302 | Anti-Rat MCL1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC710 | CytoStream™ Rabbit Anti-MCL1 Recombinant Antibody (VS13-YC710) | WB, ICC, IF, IHC-P, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
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