Human Anti-AChR Recombinant Antibody (clone 131) (CAT#: VS-0723-CJ38)
This product recognizes human AchR. IgG1-131 binds the γ-subunit of fetal AChR with high specificity and sub-nanomolar apparent affinity. Mab 131 blocked one of the two α-bungarotoxin binding sites on the fetal AChR, and partially blocked the binding of an antibody (mAb 637) to the α-subunit of the AChR. mAb 131 does not cross-react with AChRs of mouse, rat or rhesus monkey muscle and also does not bind to AChR from Torpedo electric organ which is of the gamma type (independent of development).
Specific Inquiry
Specifications
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Human AchR
- Species Reactivity
- Human
- Clone
- 131
- Applications
- ELISA, WB, IF, Inhib, DB
- Conjugate
- Unconjugated
- Related Disease
- Myasthenia gravis; Rhabdomyosarcoma; Arthrogryposis multiplex congenita
Product Property
- Purification
- Protein A purified
- Purity
- >95%
- Buffer
- PBS
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- mAb 131 did not reduce fetal AChR ion channel currents in electrophysiological experiments. mAb 131 did not the adult type AChR and the gamma type AChR (independent of development).
Target
- Alternative Names
- Alpha subunit of the acetylcholine receptor
Recommended Products
Isotype Control
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "AChR"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-33 | Recombinant Anti-AChR Antibody | ELISA, WB, IF, FuncS | IgG |
| MHH-33 | Recombinant Human Anti-AChR Antibody | ELISA, WB, IP, FuncS | IgG |
| FAMAB-0223YC | Rat Anti-AChR Recombinant Antibody (clone mAb 192) | FuncS | Rat IgG2b |
| FAMAB-0224YC | Rat Anti-AChR Recombinant Antibody (clone mAb 195) | FuncS | Rat IgG1 |
| FAMAB-0001WJ | Human Anti-AChR Recombinant Antibody (clone 587) | RIA, IP, IF | Human IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-33-F(E) | Recombinant Anti-AChR Antibody Fab Fragment | IP, FuncS | Fab |
| MHH-33-F(E) | Recombinant Human Anti-AChR Antibody Fab Fragment | IF, ELISA, FuncS | Fab |
| FAMAB-0223-YC-F(E) | Rat Anti-AChR Recombinant Antibody (clone mAb 192); Fab Fragment | FuncS | Rat Fab |
| FAMAB-0224-YC-F(E) | Rat Anti-AChR Recombinant Antibody (clone mAb 195); Fab Fragment | FuncS | Rat Fab |
| FAMAB-0001WJ-F(E) | Human Anti-AChR Recombinant Antibody (clone 587); Fab Fragment | RIA, IP, IF | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-007 | Rat Anti-AChR Recombinant Antibody (clone mAb192); scFv Fragment | WB, FuncS | Rat scFv |
| PSBZ-007 | Rat Anti-AChR Recombinant Antibody (clone mAb198); scFv Fragment | WB, ELISA | Rat scFv |
| FAMAB-0001WJ-S(P) | Human Anti-AChR Recombinant Antibody (clone 587); scFv Fragment | RIA, IP, IF | Human scFv |
| FAMAB-0002WJ-S(P) | Human Anti-AChR Recombinant Antibody (clone 637); scFv Fragment | RIA, IP, IF | Human scFv |
| FAMAB-0029WJ-S(P) | Human Anti-AChR Recombinant Antibody (clone MH6); scFv Fragment | ELISA | Human scFv |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0636CLV | Anti-Human AChR Recombinant Antibody (P90-131) | WB | Fully Human antibody |
| TAB-0637CLV | Anti-Human AChR Recombinant Antibody (P90-65) | RIA, IF | Fully Human antibody |
| TAB-0638CLV | Human Anti-AChR Recombinant Antibody (TAB-0638CLV) | Dot, FuncS, IF | Human IgG1 |
| TAB-0639CLV | Human Anti-AChR Recombinant Antibody (TAB-0639CLV) | RIA, IF | Human IgG |
| TAB-0638CLV-S(P) | Human Anti-AChR Recombinant Antibody; scFv Fragment (TAB-0638CLV-S(P)) | ELISA | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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