Human Anti-AChR Recombinant Antibody (clone 131) (CAT#: VS-0723-CJ38)
This product recognizes human AchR. IgG1-131 binds the γ-subunit of fetal AChR with high specificity and sub-nanomolar apparent affinity. Mab 131 blocked one of the two α-bungarotoxin binding sites on the fetal AChR, and partially blocked the binding of an antibody (mAb 637) to the α-subunit of the AChR. mAb 131 does not cross-react with AChRs of mouse, rat or rhesus monkey muscle and also does not bind to AChR from Torpedo electric organ which is of the gamma type (independent of development).
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Specifications
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Human AchR
- Species Reactivity
- Human
- Clone
- 131
- Applications
- ELISA, WB, IF, Inhib, DB
- Conjugate
- Unconjugated
- Related Disease
- Myasthenia gravis; Rhabdomyosarcoma; Arthrogryposis multiplex congenita
Product Property
- Purification
- Protein A purified
- Purity
- >95%
- Buffer
- PBS
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- mAb 131 did not reduce fetal AChR ion channel currents in electrophysiological experiments. mAb 131 did not the adult type AChR and the gamma type AChR (independent of development).
Target
- Alternative Names
- Alpha subunit of the acetylcholine receptor
Recommended Products
Isotype Control
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-33 | Recombinant Anti-AChR Antibody | ELISA, WB, IF, FuncS | IgG |
| PABC-007 | Rat Anti-AChR Recombinant Antibody (clone mAb192) | WB, FuncS | Rat IgG2b, κ |
| PABZ-007 | Rat Anti-AChR Recombinant Antibody (clone mAb198) | WB, ELISA | Rat IgG |
| MOB-082CQ | Mouse Anti-AChR Recombinant Antibody (clone mAb192) | ELISA, WB, Block | Mouse IgG2a, κ |
| VS-0723-CJ5 | Mouse Anti-AChR Recombinant Antibody (clone 35) | Inhib, IHC | Mouse IgG |
Customer Reviews and Q&As
Customer Review
Q&As
Superior blocking optimization
With proper blocking steps, the antibody provided clean results. Effective against background issues in various experimental setups.
Robust and reliable
The robustness of this antibody has made it a reliable tool across multiple projects. It's consistently dependable.
Multi-species reactivity
Validated this antibody in different cell lines, and it maintained high reactivity and specificity. Truly versatile.
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For Research Use Only. Not For Clinical Use.
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