AbPlus™ Anti-ADGRE5 Magnetic Beads (VS-0724-YC456) (CAT#: VS-0724-YC456)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-ADGRE5 specific antibody

• Target
• ADGRE5

• Immunogen
• Recombinant human CD97, aa 1-398.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011]

• Alternative Names
• Adhesion G Protein-Coupled Receptor E5; Leukocyte Antigen CD97; CD97 Antigen; Seven-Transmembrane, Heterodimeric Receptor Associated With Inflammation; Seven Transmembrane Helix Receptor; Seven-Span Transmembrane Protein; CD97 Molecule; TM7LN1; CD97;

• Gene ID
• 976

• UniProt ID
• P48960

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