Rabbit Anti-APLP2 Recombinant Antibody (clone R06-8I7) (CAT#: VS3-FY1971)
The R06-8I7 recombinant monoclonal antibody has been developed to detect human APLP2. It cross-reacts with rat. The APLP2 antibody has been teted positive by western blot analysis of APLP2 in rat brain lysates.
Specific Inquiry
WB
Figure 1 Anti-APLP2 Antibody (VS3-FY1971) in WB.
The APLP2 expression in rat brain lysates were detected using the anti-APLP2 by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human APLP2
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Rat APLP2
- Species Reactivity
- Human, Rat
- Clone
- R06-8I7
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 87 kDa, while the observed molecular weight stands at 115 kDa.
- Related Disease
- Alzheimer's diseases
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Amyloid Beta Precursor Like Protein 2; Amyloid Beta (A4) Precursor-Like Protein 2; CDEI Box-Binding Protein; APLP-2; APPL2; CDEBP
- Gene ID
- 334
- UniProt ID
- Q06481
- Sequence Similarities
- Belongs to the APP family.
- Cellular Localization
- Cell membrane, Membrane, Nucleus
- Post Translation Modifications
- The BPTI/Kunitz inhibitor domain is O-glycosylated. (Q06481-APLP2_HUMAN)
Glycosylation at Thr380, Ser381, Asn541, Thr367, Thr371, and Thr658 (NX_Q06481 [NX_Q06481-1])
Ubiquitination at Lys744 and Lys756 (NX_Q06481 [NX_Q06481-1])
Modification sites at PhosphoSitePlus (Q06481)
Glycosylation from GlyConnect APLP2_HUMAN (1008)
Glycosylation from GlyGen (Q06481) 10 sites, 4 N-linked glycans (1 site), 2 O-linked glycans (8 sites)
- Protein Refseq
- NP_001135748.1; NP_001135749.1; NP_001135750.1; NP_001230228.1; NP_001315611.1
- Function
- May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0203 | Hi-Affi™ Rabbit Anti-APLP2 Recombinant Antibody (clone DS203AB) | IHC-P, WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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