Mouse Anti-CAPN2 Recombinant Antibody (VS3-FY2643) (CAT#: VS3-FY2643)
The anti-CAPN2 antibody is a mouse recombinant monoclonal antibody, which has been intricately crafted to target the CAPN2. The calculated molecular weight of the antigen is 80.0 kDa. It cross-reacts with human and mouse. This monoclonal antibody is potential for conducting research on Alzheimer's disease. This monoclonal antibody can be used in Western Blot, Immunohistochemistry, Flow cytometry.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/if_selected.jpg
Figure 2 IHC staining of human urinary bladder
(Immunohistochemical staining of human urinary bladder shows moderate positivity in subsets of urothelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/ihc_selected.jpg
(Immunohistochemical staining of human urinary bladder shows moderate positivity in subsets of urothelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/ihc_selected.jpg
Figure 3 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/53623_B_7_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/53623_B_7_5.jpg
Figure 4 Bronchus
(Respiratory epithelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/53623_B_5_2.jpg
(Respiratory epithelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/53623_B_5_2.jpg
Figure 5 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/53623_A_8_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24470/53623_A_8_5.jpg
Figure 6 RNA cell line category: Cell line enhanced (TIME)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000162909-CAPN2
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000162909-CAPN2
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Calpain 2 of human and mouse origins
- Species Reactivity
- Human, Mouse
- Applications
- WB, IHC, FC
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 80.0 kDa.
- Related Disease
- Alzheimer's disease
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/200
Flow cytometry: 1/50-1/100
Target
- Alternative Names
- Calpain 2; Calcium-Activated Neutral Proteinase 2; Calpain 2, (M/II) Large Subunit; Millimolar-Calpain; Calpain M-Type; EC 3.4.22.53; M-Calpain; CANP 2; CANPL2; Calpain 2, Large [Catalytic] Subunit
- Gene ID
- 824
- UniProt ID
- P17655
- Sequence Similarities
- Belongs to the peptidase C2 family.
- Cellular Localization
- Cytoplasm
Cell membrane
- Post Translation Modifications
- Ubiquitination at Lys26, Lys260, Lys476, and Lys674
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_047287300.1; XP_054194910.1; NP_001139540.1; NP_001739.3
- Function
- Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
Proteolytically cleaves MYOC at 'Arg-226'
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CAPN2"
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2088z | Mouse Anti-CAPN2 Recombinant Antibody (clone 3B9) | ELISA, WB | Mouse IgG1 |
| MRO-0217-CN | Rabbit Anti-CAPN2 Recombinant Antibody (clone JA43-41) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-QX151 | Mouse Anti-CAPN2 Recombinant Antibody (clone 1381CT669.7.66.71) | WB, IHC, FC | Mouse IgG2b |
| VS3-CJ717 | Mouse Anti-CAPN2 Recombinant Antibody (VS3-CJ717) | WB, IHC-P, FC | Mouse IgG2b |
| VS4-WK59 | Rabbit Anti-CAPN2 Recombinant Antibody (clone 17E9) | ELISA, WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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