Human Anti-CD34 Recombinant Antibody; scFv Fragment (HPAB-0884-WJ-S(P)) (CAT#: HPAB-0884-WJ-S(P))
This is a humanized monoclonal antibody, HPAB-0884-WJ, that targets CD34, a surface antigen found on human stem cells. The binding affinity of HPAB-0884-WJ to KG1a cells was determined to be 6.9 nM, as measured by the KD value. HPAB-0884-WJ-S(P) antibody is the scfv fragment antibody form of HPAB-0884-WJ antibody. Single-chain variable fragments (scFvs) are artificial constructs consisting of the variable regions of the immunoglobulin heavy and light chains connected by a peptide linker.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line HUVEC TERT2 shows localization to nucleoplasm & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36723/1751_G1_7_cr57fd220c70be0_selected.jpg
(Immunofluorescent staining of human cell line HUVEC TERT2 shows localization to nucleoplasm & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36723/1751_G1_7_cr57fd220c70be0_selected.jpg
Figure 2 Cerebral cortex
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18/155469_B_8_5.jpg
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18/155469_B_8_5.jpg
Figure 3 Colon
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18/155469_A_9_3.jpg
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18/155469_A_9_3.jpg
Figure 4 Kidney
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18/155469_A_8_5.jpg
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18/155469_A_8_5.jpg
Figure 5 RNA cell line category: Group enriched (HUVEC TERT2, MOLT-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000174059-CD34
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000174059-CD34
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized scFv
- Specificity
- Human CD34
- Species Reactivity
- Human
- Applications
- ELISA
- Related Disease
- Malignant hematologic diseases, Solid tumors.
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CD34; CD34 molecule; hematopoietic progenitor cell antigen CD34; CD34 antigen
- Gene ID
- 947
- UniProt ID
- P28906
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CD34"
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-175-S(P) | Recombinant Anti-human CD34 Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
| MHH-175-S(P) | Recombinant Human Anti-human CD34 Antibody scFv Fragment | WB, Neut, FuncS | scFv |
| HPAB-1042-FY-F(E) | Mouse Anti-CD34 Recombinant Antibody (clone c4C8); scFv Fragment | ELISA | Mouse scFv |
| HPAB-1043-FY-F(E) | Mouse Anti-CD34 Recombinant Antibody (clone C5B12); scFv Fragment | ELISA | Mouse scFv |
| HPAB-1044-FY-F(E) | Mouse Anti-CD34 Recombinant Antibody (clone C2e10); scFv Fragment | ELISA | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-175-F(E) | Recombinant Human Anti-human CD34 Antibody Fab Fragment | Neut, IF, FuncS | Fab |
| HPAB-M0472-YC-F(E) | Mouse Anti-CD34 Recombinant Antibody; Fab Fragment (HPAB-M0472-YC-F(E)) | WB, IF, IHC, IP, WB | Mouse Fab |
| HPAB-M0473-YC-F(E) | Human Anti-CD34 Recombinant Antibody; Fab Fragment (HPAB-M0473-YC-F(E)) | ELISA | Chimeric (mouse/human) Fab |
| HPAB-M0474-YC-F(E) | Human Anti-CD34 Recombinant Antibody; Fab Fragment (HPAB-M0474-YC-F(E)) | ELISA | Humanized Fab |
| HPAB-1042-FY-S(P) | Human Anti-CD34 Recombinant Antibody (clone c4C8); Fab Fragment | ELISA | Chimeric (mouse/human) Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-149LC | Anti-Human CD34 Recombinant Antibody (h4C8) | FC, Inhib | Humanized antibody |
| TAB-149LC-S(P) | Anti-Human CD34 Recombinant Antibody scFv Fragment (h4C8) | ELISA | Humanized antibody |
| TAB-149LC-F(E) | Anti-Human CD34 Recombinant Antibody Fab Fragment (h4C8) | ELISA | Humanized antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-150LC | Human Anti-CD34 Recombinant Antibody (TAB-150LC) | ELISA | Human IgG |
| TAB-150LC-S(P) | Human Anti-CD34 Recombinant Antibody; scFv Fragment (TAB-150LC-S(P)) | ELISA | Human scFv |
| TAB-150LC-F(E) | Human Anti-CD34 Recombinant Antibody; Fab Fragment (TAB-150LC-F(E)) | ELISA | Human Fab |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-342CQ | Mouse Anti-CD34 Recombinant Antibody (clone 4H11) | Block, FC, IF | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0554 | Hi-Affi™ Rabbit Anti-CD34 Recombinant Antibody (clone DS554AB) | IHC-P, IP, WB | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0883-WJ | Mouse Anti-CD34 Recombinant Antibody (HPAB-0883-WJ) | ELISA | Mouse IgG |
| HPAB-0884-WJ | Human Anti-CD34 Recombinant Antibody (HPAB-0884-WJ) | ELISA | Humanized IgG |
| FAMAB-1046CQ | Mouse Anti-CD34 Recombinant Antibody (clone My10) | IP, FC, IHC | Mouse IgG1 |
| FAMAB-1047CQ | Human Anti-CD34 Recombinant Antibody (clone 5B12) | WB, FC | Human IgG1 |
| FAMAB-1048CQ | Human Anti-CD34 Recombinant Antibody (clone 4C8) | WB, FC | Human IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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