Human Anti-CFB Recombinant Antibody (clone AAfBb)
CAT#: HPAB-M0511-YC
Provided is an aglycosylated humanized anti-Bb (AAfBb) antibody includes a modification at a conserved N-linked site in the CH2 domains of an Fc portion of the antibody. AAfBb antibody is a specific inhibitor of the AP and does not inhibit or activate the classical pathway. AAfBb antibody binds to Bb so as to prevent cleavage of Factor B to produce Bb when present in the complex PC3bB.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to cell junctions.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/951/170_F11_1_selected.jpg
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Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG
- Specificity
- Human CFB
- Species Reactivity
- Human
- Clone
- AAfBb
- Applications
- ELISA, Inhib
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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- CAT
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
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| MOB-2492z | Mouse Anti-CFB Recombinant Antibody (clone 37A3) | WB, ELISA, FC, IHC, FuncS | Mouse IgG1 |
| HPAB-AP040-YC | Human Anti-CFB Recombinant Antibody (HPAB-AP040-YC) | ELISA | Human IgG |
| HPAB-AP041-YC | Human Anti-CFB Recombinant Antibody (HPAB-AP041-YC) | ELISA | Human IgG |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-059MZ | Anti-Human CFB Recombinant Antibody (FB-28.4.2) | ELISA, WB | |
| TAB-060MZ | Mouse Anti-CFB Recombinant Antibody (TAB-060MZ) | ELISA | Mouse IgG1 |
| TAB-062MZ | Anti-Human CFB Recombinant Antibody (1F7) | ELISA | |
| TAB-059MZ-F(E) | Anti-Human CFB Recombinant Antibody Fab Fragment (FB-28.4.2) | ELISA, WB | |
| TAB-060MZ-F(E) | Mouse Anti-CFB Recombinant Antibody; Fab Fragment (TAB-060MZ-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-061MZ | Human Anti-CFB Recombinant Antibody (TAB-061MZ) | ELISA | Humanized antibody |
| TAB-061MZ-S(P) | Human Anti-CFB Recombinant Antibody; scFv Fragment (TAB-061MZ-S(P)) | ELISA | Humanized scFv |
| TAB-061MZ-F(E) | Human Anti-CFB Recombinant Antibody; Fab Fragment (TAB-061MZ-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0673 | Hi-Affi™ Rabbit Anti-CFB Recombinant Antibody (clone DS673AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0145CQ-F(E) | Human Anti-CFB Recombinant Antibody; Fab Fragment (HPAB-0145CQ-F(E)) | ELISA, Inhib, FC | Humanized Fab |
| HPAB-0146CQ-F(E) | Mouse Anti-CFB Recombinant Antibody; Fab Fragment (HPAB-0146CQ-F(E)) | ELISA, Inhib, FC | Mouse Fab |
| HPAB-0119-YJ-F(E) | Human Anti-CFB Recombinant Antibody; Fab Fragment (HPAB-0119-YJ-F(E)) | FuncS, Inhib, Block | Humanized Fab |
| HPAB-M0511-YC-F(E) | Human Anti-CFB Recombinant Antibody (clone AAfBb); Fab Fragment | ELISA, Inhib | Humanized Fab |
| FAMAB-0130WJ-F(E) | Human Anti-CFB Recombinant Antibody Fab Fragment (FAMAB-0130WJ-F(E)) | ELISA, WB, RIA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0145CQ-S(P) | Human Anti-CFB Recombinant Antibody; scFv Fragment (HPAB-0145CQ-S(P)) | ELISA, Inhib, FC | Humanized scFv |
| HPAB-0146CQ-S(P) | Mouse Anti-CFB Recombinant Antibody; scFv Fragment (HPAB-0146CQ-S(P)) | ELISA, Inhib, FC | Mouse scFv |
| HPAB-0119-YJ-S(P) | Human Anti-CFB Recombinant Antibody; scFv Fragment (HPAB-0119-YJ-S(P)) | FuncS, Inhib, Block | Humanized scFv |
| HPAB-AP279-YC-S(P) | Mouse Anti-CFB Recombinant Antibody; scFv Fragment (HPAB-AP279-YC-S(P)) | ELISA, Inhib | Mouse scFv |
| FAMAB-0130WJ-S(P) | Human Anti-CFB Recombinant Antibody scFv Fragment (FAMAB-0130WJ-S(P)) | ELISA, WB, RIA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1392 | Anti-CFB Immunohistochemistry Kit | IHC |
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