Human Anti-CHIKV E2 Recombinant Antibody (clone ch-CHK-152); Fab Fragment (CAT#: HPAB-S0184-YC-F(E))
A chimeric mouse-human CHK-152 (ch-CHK-152) was derived from murine antibody CHK-152. The affinity of ch-CHK-152 binding to purified pE2-E1 was measured by surface plasmon resonance (SPR) and compared to the parent murine MAb. Notably, ch-CHK-152 and the murine CHK-152 all had similar affinity (KD of 3 to 4 nM) and neutralizing activity in cell culture.
Specific Inquiry
Specifications
- Immunogen
- Adult C57BL/6 mice deficient for interferon regulatory factor 7 (Irf7 −/−) were infected with the La Reunion 2006 OPY-1 strain of CHIKV (CHIKV-LR). These mice were boosted with CHIK virus-like particles, soluble recombinant CHIKV E2 protein, or live CHIKV-LR.
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Human Fab
- Specificity
- CHIKV E2
- Species Reactivity
- CHIKV
- Clone
- ch-CHK-152
- Applications
- Neut, FRNT, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Chikungunya virus E2 protein
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
Mouse Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-430 | Recombinant Human Anti-CHIKV E2 Antibody (PABL-430) | IB, ELISA, BL | IgG |
| PABL-431 | Recombinant Mouse Anti-CHIKV E2 Antibody (CHK9) | Neut, BL | IgG |
| MOB-152CQ | Mouse Anti-CHIKV E2 Antibody (CHK265) | Neut, ELISA, IF, FC | Mouse IgG1, λ |
| HPAB-S0184-YC | Human Anti-CHIKV E2 Recombinant Antibody (clone ch-CHK-152) | Neut, FRNT, FuncS | Human IgG |
| HPAB-S0185-YC | Human Anti-CHIKV E2 Recombinant Antibody (clone ch-CHK-152 N297Q) | Neut, FRNT, FuncS | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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