Human Anti-CLDN4 Antibody (Humanized KM3900), CHO Stable Cell Pool
CAT#: VS-1025-QX240
This CHO Stable Cell Pool represents a genetically engineered Chinese Hamster Ovary (CHO) cell population specifically designed for the robust and consistent expression of recombinant Humanized KM3900. Humanized KM3900 is a Human monoclonal antibody that targets CLDN4. This cell pool was generated through the stable integration of genes encoding the heavy and light chains of Humanized KM3900 into the CHO genome, followed by selection and enrichment for high-expressing cells. This cell pool provides rapid production of research-grade antibodies for non-GLP preclinical studies.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2610/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2610/6439_B_7_5.jpg
Normal Tissue
Figure 3 Esophagus
Squamous epithelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2610/6439_B_6_1.jpg
Normal Tissue
Figure 4 High expression in colon.
Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2610/6439_A_7_3.jpg
Normal Tissue
Figure 5 Kidney
Collecting ducts Staining: Medium Intensity: Strong Quantity: <25% Distal tubules Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2610/6439_A_8_5.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (A-431, BEWO, CAPAN-2, MCF7, OE19, PC-3, RT4, SK-BR-3)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000189143-CLDN4
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Specifications
- Host Cell
- CHO
- Product Type
- Stable Cell Pool
- Cell Viability
- >90%
- Mycoplasma Detection
- Negative
- Bacteria Detection
- Negative
- Growth Properties
- Suspension
- Culture Medium
- VersaCHO™ Medium (VS-1025-QX582)
- Complete Growth Medium
- VersaCHO™ Medium (VS-1025-QX582), VersaCHO™ Feed Medium (VS-1025-QX583), VersaCHO™ Feed Supplement (VS-1025-QX584)
- Freeze Medium
- 90% VersaCHO™ Medium, 10% DMSO
- Growth Conditions
- 37°C, 5% CO₂
- Size
- Each vial contains at least 1×10^6 cells in 1 mL
- Shipping
- Dry ice
- Storage
- Store in liquid nitrogen immediately upon receipt. Avoid multiple freeze/thaw cycles. Utilize cells within one year of the delivery date.
Antibody Overview
- Host Species
- Human
- Antibody Type
- Human IgG1, κ
- Clone
- Humanized KM3900
- Target
- CLDN4
- Species Reactivity
- Human
Target
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Datasheet
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COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "Clone Humanized KM3900"
- CAT
- Product Name
See other products for "CLDN4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3288z | Mouse Anti-CLDN4 Recombinant Antibody (clone 38H5) | IHC, IF, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-501LC | Anti-Human CLDN4 Recombinant Antibody (KM3900) | WB, IP, FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-502LC | Anti-Human CLDN4 Recombinant Antibody (cKM3900) | Cyt, FC, WB | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-503LC | Anti-Human CLDN4 Recombinant Antibody (Humanized KM3900) | Cyt, FC, WB | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-504LC | Anti-Human CLDN4 Recombinant Antibody (KM3907) | Cyt, FC, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-505LC | Anti-Human CLDN4 Recombinant Antibody (cKM3907) | Cyt, FC, WB | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-506LC | Anti-Human CLDN4 Recombinant Antibody (TAB-506LC) | FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-501LC-S(P) | Anti-Human CLDN4 Recombinant Antibody scFv Fragment (KM3900) | WB, IP |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-504LC-S(P) | Anti-Human CLDN4 Recombinant Antibody scFv Fragment (KM3907) | WB, IP |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-0160J | Mouse Anti-CLDN4 Recombinant Antibody (ZG-0160J) | IHC-P, IF | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-0161J | Mouse Anti-CLDN4 Recombinant Antibody (ZG-0161J) | IHC-P, IF | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-0618J | Rabbit Anti-CLDN4 Recombinant Antibody (clone 2G12) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-CJ119 | Mouse Anti-CLDN4 Recombinant Antibody (clone ABT-CLD4) | WB, IHC-P | Mouse IgG2b, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC131 | Recombinant Anti-CLDN4 Vesicular Antibody, EV Displayed (VS-0425-YC131) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1487 | Anti-CLDN4 Immunohistochemistry Kit | IHC |
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