Human Anti-CSF2 Recombinant Antibody (clone hGM4/35); Fab Fragment (CAT#: HPAB-0014-FY-F(E))
Recombinant Fab fragment to CSF2. This product is a recombinant human antibody that recognizes human CSF2. Antibody hGM4/35 also neutralizes each of the 1001 and 100T variants of human GM-CSF in an IL-8 secretion assay in U937 cells.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57404/1703_H9_1_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57404/1703_H9_1_selected.jpg
Figure 2 RNA cell line category: Cell line enriched (BJ hTERT+)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164400-CSF2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164400-CSF2
Figure 2 RNA cell line category: Cell line enriched (BJ hTERT+)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164400-CSF2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164400-CSF2
Specifications
- Immunogen
- Humanized monoclonal antibody (hGM4/34) variant, comprising a H98Y mutation in the CDR3 region of variable light chain (VL), targeting 100I and 100T variants of human granulocyte-macrophage colony stimulating factor (hGM-CSF)
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human CSF2
- Species Reactivity
- Human
- Clone
- hGM4/35
- Applications
- ELISA
- Related Disease
- Diagnostic Agents, Inflammation, Autoimmune Diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Colony Stimulating Factor 2; Molgramostin; Colony Stimulating Factor 2 (Granulocyte-Macrophage); GMCSF; CSF
- Gene ID
- 1437
- UniProt ID
- P04141
Related Resources
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Fab Fragment Antibody
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1257z | Mouse Anti-CSF2 Recombinant Antibody (clone 21C4) | WB, ELISA, IHC, FuncS | Mouse IgG1 |
| FN-240CQ | Mouse Anti-Csf2 Recombinant Antibody (clone CBL-1345) | Block, FuncS | Mouse IgG1, κ |
| HPAB-N0052-YC | Human Anti-CSF2 Recombinant Antibody (HPAB-N0052-YC) | ELISA, Block | Humanized IgG |
| FAMAB-1100CQ | Human Anti-CSF2 Recombinant Antibody (clone GCC21) | Neut, ELISA | Human IgG1 |
| VS3-XY537 | Mouse Anti-CSF2 Recombinant Antibody (clone 3D3) | ELISA, WB | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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