Human Anti-CXCL8 Recombinant Antibody (clone K4.3) (CAT#: HPAB-A1378-YJ)
This product is a Human antibody that recognizes CXCL8.
Specific Inquiry
Inhib
Figure 1 Inhibition of IL-8 binding to human neutrophils by anti-IL-8 mAbs.
Yang, X. D., Corvalan, J. R., Wang, P., Roy, C. M., & Davis, C. G. (1999). Fully human anti-interleukin-8 monoclonal antibodies: potential therapeutics for the treatment of inflammatory disease states. Journal of Leukocyte Biology, 66(3), 401-410.
FuncS
Figure 2 Inhibition of skin inflammation in rabbits by K4.3
Yang, X. D., Corvalan, J. R., Wang, P., Roy, C. M., & Davis, C. G. (1999). Fully human anti-interleukin-8 monoclonal antibodies: potential therapeutics for the treatment of inflammatory disease states. Journal of Leukocyte Biology, 66(3), 401-410.
SPR
Figure 3 Affinity Constants of the Fully Human IL-8 Antibodies.
Yang, X. D., Corvalan, J. R., Wang, P., Roy, C. M., & Davis, C. G. (1999). Fully human anti-interleukin-8 monoclonal antibodies: potential therapeutics for the treatment of inflammatory disease states. Journal of Leukocyte Biology, 66(3), 401-410.
Specifications
- Host Species
- Human
- Type
- Human lgG2
- Specificity
- Human CXCL8
- Species Reactivity
- Human
- Clone
- K4.3
- Applications
- ELISA, Inhib, Neut, FuncS, SPR
- Related Disease
- Tumor
Product Property
- Purification
- Protein A/G Purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the Certificate of Analysis for the lot-specific concentration.
- Buffer
- PBS
- Storage
- Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Applications
- Application Notes
- This antibody can be used in Enzyme-linked Immunosorbent Assay, Inhibition, Neutralization, Founctional Assay, and Surface Plasmon Resonance. Optimal working dilutions should be determined experimentally by the investigator.
Target
- Alternative Names
- IL8; NAF; GCP1; LECT; LUCT; NAP1; GCP-1; LYNAP; MDNCF; MONAP; NAP-1; SCYB8; interleukin-8; T-cell chemotactic factor; alveolar macrophage chemotactic factor I; beta endothelial cell-derived neutrophil activating peptide; beta-thromboglobulin-like protein; chemokine (C-X-C motif) ligand 8; emoctakin; granulocyte chemotactic protein 1; interleukin 8; lung giant cell carcinoma-derived chemotactic protein; lymphocyte derived neutrophil activating peptide; monocyte-derived neutrophil chemotactic factor; monocyte-derived neutrophil-activating peptide; neutrophil-activating peptide 1; small inducible cytokine subfamily B, member 8; tumor necrosis factor-induced gene 1
- Gene ID
- 3576
- UniProt ID
- P10145
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CXCL8"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-738-sdAb | Recombinant Anti-human CXCL8 VHH Single Domain Antibody | IHC, ICC, FC, FA, FUNC | Llama VHH |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-201CL | Human Anti-CXCL8 Recombinant Antibody (TAB-201CL) | ELISA | Human IgG2 |
| TAB-701LC | Human Anti-CXCL8 Recombinant Antibody (TAB-701LC) | ELISA, FC, FuncS | Human IgG1, κ |
| TAB-701LC-S(P) | Human Anti-CXCL8 Recombinant Antibody; scFv Fragment (TAB-701LC-S(P)) | ELISA | Human scFv |
| TAB-701LC-F(E) | Human Anti-CXCL8 Recombinant Antibody; Fab Fragment (TAB-701LC-F(E)) | ELISA | Human Fab |
Fc Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-095LC | Recombinant Anti-Human CXCL8 Antibody (Fc glycosylation) | ELISA | Humanized antibody |
Deglycosylated Antibody (Non-glycosylated IgGs)
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-164LC | Recombinant Anti-Human CXCL8 Antibody (Non-glycosylated) | ELISA | Mouse antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-644CQ | Mouse Anti-CXCL8 Recombinant Antibody (clone CBL601) | ELISA, Neut | Mouse IgG1 |
| NEUT-645CQ | Mouse Anti-CXCL8 Recombinant Antibody (clone CBL602) | WB, ICC, Neut | Mouse IgG1 |
| NEUT-646CQ | Mouse Anti-CXCL8 Recombinant Antibody (clone CBL115) | FC, WB, IHC, Neut | Mouse IgG1 |
| NEUT-647CQ | Mouse Anti-CXCL8 Recombinant Antibody (clone I8-60) | ELISA, Neut, WB | Mouse IgG1, κ |
| NEUT-648CQ | Mouse Anti-CXCL8 Recombinant Antibody (clone I8-S2) | ELISA, Neut, WB | Mouse IgG2b, κ |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-660CQ | Mouse Anti-CXCL8 Recombinant Antibody (clone B-K8) | Block, ICFC | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4128 | Hi-Affi™ Rabbit Anti-CXCL8 Recombinant Antibody (clone SI199DS) | ELISA | Rabbit IgG |
| MOR-4624 | Hi-Affi™ Rabbit Anti-CXCL8 Recombinant Antibody (clone TH137DS) | WB | Rabbit IgG |
| MOR-4625 | Hi-Affi™ Rabbit Anti-CXCL8 Recombinant Antibody (clone TH138DS) | WB | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0059-YC-S(P) | Human Anti-CXCL8 Recombinant Antibody; scFv Fragment (HPAB-N0059-YC-S(P)) | FuncS | Human scFv |
| HPAB-1682-FY-F(E) | Human Anti-CXCL8 Recombinant Antibody; Fab Fragment (HPAB-1682-FY-F(E)) | ELISA | Human Fab |
| HPAB-1683-FY-F(E) | Human Anti-CXCL8 Recombinant Antibody; Fab Fragment (HPAB-1683-FY-F(E)) | ELISA | Human Fab |
| HPAB-1684-FY-F(E) | Human Anti-CXCL8 Recombinant Antibody; Fab Fragment (HPAB-1684-FY-F(E)) | ELISA | Human Fab |
| HPAB-1310WJ-S(P) | Human Anti-CXCL8 Recombinant Antibody (clone M1-10); scFv Fragment | ELISA | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1101-FY-S(P) | Mouse Anti-CXCL8 Recombinant Antibody (clone 656.35); Fab Fragment | ELISA, IA, Block | Mouse Fab |
| HPAB-1102-FY-S(P) | Mouse Anti-CXCL8 Recombinant Antibody (clone 197.2); Fab Fragment | ELISA, IA, Block | Mouse Fab |
| HPAB-1103-FY-S(P) | Mouse Anti-CXCL8 Recombinant Antibody (clone 81.1); Fab Fragment | ELISA, IA, Block | Mouse Fab |
| HPAB-1104-FY-S(P) | Mouse Anti-CXCL8 Recombinant Antibody; scFv Fragment (HPAB-1104-FY-S(P)) | ELISA | Mouse scFv |
| HPAB-1682-FY-S(P) | Human Anti-CXCL8 Recombinant Antibody; scFv Fragment (HPAB-1682-FY-S(P)) | ELISA | Human scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1682-FY | Human Anti-CXCL8 Recombinant Antibody (HPAB-1682-FY) | ELISA | Human IgG |
| HPAB-1683-FY | Human Anti-CXCL8 Recombinant Antibody (HPAB-1683-FY) | ELISA | Human IgG |
| HPAB-1684-FY | Human Anti-CXCL8 Recombinant Antibody (HPAB-1684-FY) | ELISA | Human IgG |
| HPAB-0664-YJ | Mouse Anti-CXCL8 Recombinant Antibody (clone 5.12.14) | ELISA, WB, Inhib, Antagonist | Mouse IgG2a |
| HPAB-0665-YJ | Human Anti-CXCL8 Recombinant Antibody (clone ch5.12.14) | ELISA, WB, Inhib, Antagonist | Chimeric (mouse/human) IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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