Human Anti-CXCL8 Recombinant Antibody (clone WS-4) (CAT#: HPAB-1841-FY)

This product is a recombinant antibody that recognizes CXCL8. The monoclonal antibody WS-4 reacts with the epitope of CXCL8. WS-4 has been shown to inhibit the binding of rabbit IL-8 to rabbit neutrophils by Harada.

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  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
ELISA

Figure 3 Shows a graph showing a result of ELISA for confirmation of an ability to bind to human IL-8 of the chimeric WS-4 antibody (chL/chH) produced in the supernatant of COS cells.

Figure 3 Shows a graph showing a result of ELISA for confirmation of an ability to bind to human IL-8 of the chimeric WS-4 antibody (chL/chH) produced in the supernatant of COS cells.

Block

Figure 4 Shows a graph showing the results of a receptor binding inhibition assay.

Figure 4 Shows a graph showing the results of a receptor binding inhibition assay.

This assay tests the ability of purified control human IgG, a chimeric antibody (chL/chH), reshaped antibodies (RVLa/RVHg and RVLb/RVHg) and the original WS-4 antibody to block binding of IL-8 to its receptor.


Specifications

  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • Human IgG
  • Specificity
  • Human CXCL8
  • Species Reactivity
  • Human
  • Clone
  • WS-4
  • Applications
  • Inhib, FC, ELISA, Block
  • Related Disease
  • Crohn's Disease, inflammatory bowel disease

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The CXCL8 antibody has been reported in applications of Inhibition, Flow Cytometry, Enzyme-linked Immunosorbent Assay, Blocking.

Target

  • Alternative Names
  • IL8; NAF; GCP1; LECT; LUCT; NAP1; GCP-1; LYNAP; MDNCF; MONAP; NAP-1; interleukin-8; T-cell chemotactic factor; alveolar macrophage chemotactic factor I; beta endothelial cell-derived neutrophil activating peptide; beta-thromboglobulin-like protein; chemokine (C-X-C motif) ligand 8; emoctakin; granulocyte chemotactic protein 1; interleukin 8; lung giant cell carcinoma-derived chemotactic protein; lymphocyte derived neutrophil activating peptide; monocyte-derived neutrophil chemotactic factor; monocyte-derived neutrophil-activating peptide; neutrophil-activating peptide 1; small inducible cytokine subfamily B, member 8; tumor necrosis factor-induced gene 1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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CAT Product Name Application Type
NAB-738-sdAb Recombinant Anti-human CXCL8 VHH Single Domain Antibody IHC, ICC, FC, FA, FUNC Llama VHH

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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