Recombinant Anti-DLL3 (DSL domain x EGF-like domain) Biparatopic Antibody, Tandem scFv (CAT#: VS-0525-YC48)
The recombinant Anti-DLL3 (DSL domain x EGF-like domain) biparatopic antibody, tandem scFv, effectively binds two distinct DLL3 epitopes. The design consists of tandem scFv arms that interact with high affinity with both the DSL domain (amino acids 176-215) and the EGF-like domain (amino acids 216-492).
Specific Inquiry
Subcellular Location
RNA Expression

Figure 1 IF staining of human cell line SK-MEL-30
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24559/1931_D10_1_selected.jpg
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24559/1931_D10_1_selected.jpg

Figure 2 IF staining of human cell line SH-SY5Y
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56533/1219_G4_3_selected.jpg
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56533/1219_G4_3_selected.jpg

Figure 3 RNA cell line category: Cell line enriched (SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000090932-DLL3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000090932-DLL3
Specifications
- Host Animal 1
- Mouse
- Host Animal 2
- Mouse
- Specificity
- Human Delta-like 3
- Species Reactivity
- Human
- Type
- Tandem scFv
- Valency
- 1 + 1
- Epitope 1
- DSL domain, aa 176-215
- Epitope 2
- EGF-like domain, aa 216-492
- Purity
- >90%
- Purification
- Affinity purified
- Applications
- Cyt, ELISA, FC, Inhib
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
- Long Name
- Delta Like Canonical Notch Ligand 3
Target
- Introduction
- This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.
- Alternative Names
- DLL3; delta-like 3 (Drosophila); SCDO1; delta-like protein 3; delta3; drosophila Delta homolog 3
- Gene ID
- 10683
- UniProt ID
- Q9NYJ7
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-212MZ | Mouse Anti-DLL3 Recombinant Antibody (TAB-212MZ) | Cyt, ELISA, FC, Inhib | Mouse IgG2a |
TAB-212MZ-F(E) | Mouse Anti-DLL3 Recombinant Antibody; Fab Fragment (TAB-212MZ-F(E)) | FC, ELISA | Mouse Fab |
TAB-213MZ-F(E) | Mouse Anti-DLL3 Recombinant Antibody; Fab Fragment (TAB-213MZ-F(E)) | FC, ELISA | Mouse Fab |
TAB-214MZ-F(E) | Mouse Anti-DLL3 Recombinant Antibody; Fab Fragment (TAB-214MZ-F(E)) | FC, ELISA | Mouse Fab |
TAB-215MZ-F(E) | Mouse Anti-DLL3 Recombinant Antibody; Fab Fragment (TAB-215MZ-F(E)) | FC, ELISA | Mouse Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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