Recombinant Anti-DLL3 (DSL domain x EGF-like domain) Biparatopic Antibody, Tandem scFv
CAT#: VS-0525-YC48
The recombinant Anti-DLL3 (DSL domain x EGF-like domain) biparatopic antibody, tandem scFv, effectively binds two distinct DLL3 epitopes. The design consists of tandem scFv arms that interact with high affinity with both the DSL domain (amino acids 176-215) and the EGF-like domain (amino acids 216-492).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SK-MEL-30
Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24559/1931_D10_1_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line SH-SY5Y
Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm & plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56533/1219_G4_3_selected.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enriched (SK-MEL-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000090932-DLL3
❮
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Specifications
- Host Animal 1
- Mouse
- Host Animal 2
- Mouse
- Specificity
- Human Delta-like 3
- Species Reactivity
- Human
- Type
- Tandem scFv
- Valency
- 1 + 1
- Epitope 1
- DSL domain, aa 176-215
- Epitope 2
- EGF-like domain, aa 216-492
- Purity
- >90%
- Purification
- Affinity purified
- Applications
- Cyt, ELISA, FC, Inhib
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
- Long Name
- Delta Like Canonical Notch Ligand 3
Target
- Introduction
- This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.
- Alternative Names
- DLL3; delta-like 3 (Drosophila); SCDO1; delta-like protein 3; delta3; drosophila Delta homolog 3
- Gene ID
- 10683
- UniProt ID
- Q9NYJ7
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Datasheet
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COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-212MZ-S(P) | Mouse Anti-DLL3 Recombinant Antibody; scFv Fragment (TAB-212MZ-S(P)) | FC, ELISA | Mouse scFv |
| TAB-212MZ-F(E) | Mouse Anti-DLL3 Recombinant Antibody; Fab Fragment (TAB-212MZ-F(E)) | FC, ELISA | Mouse Fab |
| TAB-213MZ-F(E) | Mouse Anti-DLL3 Recombinant Antibody; Fab Fragment (TAB-213MZ-F(E)) | FC, ELISA | Mouse Fab |
| TAB-214MZ-F(E) | Mouse Anti-DLL3 Recombinant Antibody; Fab Fragment (TAB-214MZ-F(E)) | FC, ELISA | Mouse Fab |
| TAB-215MZ-F(E) | Mouse Anti-DLL3 Recombinant Antibody; Fab Fragment (TAB-215MZ-F(E)) | FC, ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2100LY-F(E) | Mouse Anti-DLL3 Recombinant Antibody; Fab Fragment (HPAB-2100LY-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-2101LY-F(E) | Mouse Anti-DLL3 Recombinant Antibody; Fab Fragment (HPAB-2101LY-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-2102LY-F(E) | Mouse Anti-DLL3 Recombinant Antibody; Fab Fragment (HPAB-2102LY-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-2103LY-F(E) | Mouse Anti-DLL3 Recombinant Antibody; Fab Fragment (HPAB-2103LY-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-2104LY-F(E) | Mouse Anti-DLL3 Recombinant Antibody; Fab Fragment (HPAB-2104LY-F(E)) | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2112LY | Mouse Anti-DLL3 Recombinant Antibody (HPAB-2112LY) | ELISA, FC | Mouse IgG |
| HPAB-2113LY | Mouse Anti-DLL3 Recombinant Antibody (HPAB-2113LY) | ELISA, FC | Mouse IgG |
| HPAB-2114LY | Mouse Anti-DLL3 Recombinant Antibody (HPAB-2114LY) | ELISA, FC | Mouse IgG |
| HPAB-2115LY | Mouse Anti-DLL3 Recombinant Antibody (HPAB-2115LY) | ELISA, FC | Mouse IgG |
| HPAB-2116LY | Mouse Anti-DLL3 Recombinant Antibody (HPAB-2116LY) | ELISA, FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2112LY-S(P) | Mouse Anti-DLL3 Recombinant Antibody; scFv Fragment (HPAB-2112LY-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-2113LY-S(P) | Mouse Anti-DLL3 Recombinant Antibody; scFv Fragment (HPAB-2113LY-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-2114LY-S(P) | Mouse Anti-DLL3 Recombinant Antibody; scFv Fragment (HPAB-2114LY-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-2115LY-S(P) | Mouse Anti-DLL3 Recombinant Antibody; scFv Fragment (HPAB-2115LY-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-2116LY-S(P) | Mouse Anti-DLL3 Recombinant Antibody; scFv Fragment (HPAB-2116LY-S(P)) | ELISA, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY7 | Human Anti-DLL3 scFv-Fc Chimera (VS-0325-FY7) | ADCC, FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC208 | Recombinant Anti-DLL3 Vesicular Antibody, EV Displayed (VS-0425-YC208) | Cyt, ELISA, FC, Inhib, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2017 | Anti-DLL3 Immunohistochemistry Kit | IHC |
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