Recombinant Anti-DLL3 Vesicular Antibody, EV Displayed (VS-0425-YC208) (CAT#: VS-0425-YC208)

• Application
• Cyt, ELISA, FC, Inhib, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• DLL3

• Host Animal
• Mouse

• Antibody Isotype
• IgG2a

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Delta like canonical Notch ligand 3

• Biological Process
• Differentiation, Notch signaling pathway

• Molecular Function
• Developmental protein

• Cellular Localization
• Nucleoplasm, Golgi apparatus, Plasma membrane

• Introduction
• This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.

• Alternative Names
• SCDO1

• Gene ID
• 10683

• UniProt ID
• Q9NYJ7

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