Rabbit Anti-DPYD Recombinant Antibody (clone R02-7C8)
CAT#: VS3-FY1703
The R02-7C8 recombinant monoclonal antibody reacts with human DPYD. It cross-reacts with rat. It is suitable for use in a variety of assays, including WB, IHC-F, IHC-P, ICC/IF. This DPD antibody has been teted positive by western blot analysis of DPD in C6 lysates.
Gene Expression
Tested Data
Normal Tissue
Figure 1 Lymph node
Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33241/79981_A_9_8.jpg
Normal Tissue
Figure 2 Spleen
Cells in red pulp
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33241/79981_B_9_4.jpg
RNA Expression
Figure 3 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000188641-DPYD
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WB
Figure 1 Anti-DPYD Antibody (VS3-FY1703) in WB.
The DPD expression in C6 lysates were detected using the anti-DPD by western blot assay.
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Specifications
- Immunogen
- Synthetic peptide of human DPD
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Rat DPYD
- Species Reactivity
- Human, Rat
- Clone
- R02-7C8
- Applications
- Western Blot, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunofluorescence
- MW
- The calculated weight of the target protein is approximately 111 kDa, while the observed molecular weight stands at 111 kDa.
- Related Disease
- Cancer
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Immunofluorescence: 1/50-1/200
Target
- Alternative Names
- Dihydropyrimidine Dehydrogenase; Dihydrothymine Dehydrogenase; Dihydrouracil Dehydrogenase; EC 1.3.1.2; DHPDHASE; DPD; Dihydropyrimidine Dehydrogenase [NADP(+)]; DHP
- Gene ID
- 1806
- UniProt ID
- Q12882
- Sequence Similarities
- Belongs to the dihydropyrimidine dehydrogenase family.
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- Acetylation
Phosphoprotein
- Protein Refseq
- XP_005270619.2; XP_006710460.1; XP_016855996.1; XP_047304032.1; XP_047304033.1
- Function
- Involved in pyrimidine base degradation.
Catalyzes the reduction of uracil and thymine.
Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "DPYD"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-289 | Recombinant Anti-human DPYD Antibody | ELISA, WB, IF, FuncS | IgG |
| MHH-289 | Recombinant Human Anti-human DPYD Antibody | WB, IP, FuncS | IgG |
| MOB-2088MZ | Recombinant Mouse Anti-Human DPYD Antibody (clone 7D4) | FC, ICC, IF, IHC-P, WB | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-289-F(E) | Recombinant Anti-human DPYD Antibody Fab Fragment | IF, FC, FuncS | Fab |
| MHH-289-F(E) | Recombinant Human Anti-human DPYD Antibody Fab Fragment | WB, FC, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-289-S(P) | Recombinant Anti-human DPYD Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
| MHH-289-S(P) | Recombinant Human Anti-human DPYD Antibody scFv Fragment | FC, RIA, Biosensors, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1042 | Hi-Affi™ Rabbit Anti-DPYD Recombinant Antibody (clone DS1042AB) | WB, IHC, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY693 | Anti-DPYD Immunohistochemistry Kit | IHC | |
| VS-0525-XY2076 | Anti-Human DPYD Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC321 | CytoStream™ Rabbit Anti-DPYD Recombinant Antibody (VS13-YC321) | WB, IHC-P, ICC, IF, FC | Rabbit IgG |
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