CytoStream™ Rabbit Anti-DPYD Recombinant Antibody (VS13-YC321)
CAT#: VS13-YC321
The CytoStream™ Rabbit Anti-DPYD Recombinant Antibody is specific for human DPYD. DPYD is involved in pyrimidine catabolism, impacting drug metabolism, where deficiencies cause metabolic disorders linked to cancer treatment complications. The anti-DPYD antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
Gene Expression
Normal Tissue
Figure 1 Lymph node
Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33241/79981_A_9_8.jpg
Normal Tissue
Figure 2 Spleen
Cells in red pulp
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33241/79981_B_9_4.jpg
RNA Expression
Figure 3 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000188641-DPYD
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Specifications
- Immunogen
- Recombinant human DPYD.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human DPYD
- Species Reactivity
- Human
- Applications
- WB, IHC-P, ICC, IF, FC
- Conjugate
- NONE
- Related Disease
- Cancer
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.4) containing 150 mM NaCl and 50% Glycerol.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry (IHC): 1/50-1/100
Immunofluorescence (IF): 1/50-1/200
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- Dihydropyrimidine Dehydrogenase; Dihydrothymine Dehydrogenase; Dihydrouracil Dehydrogenase; EC 1.3.1.2; DHPDHASE; DPD; Dihydropyrimidine Dehydrogenase [NADP(+)]; DHP;
- Gene ID
- 1806
- UniProt ID
- Q12882
- Long Name
- Dihydropyrimidine Dehydrogenase
- Sequence Similarities
- Belongs to the dihydropyrimidine dehydrogenase family.
- Cellular Localization
- Cytoplasm
- Protein Refseq
- XP_005270619.2; XP_006710460.1; XP_016855996.1; XP_047304032.1; XP_047304033.1
- Function
- Involved in pyrimidine base degradation.
Catalyzes the reduction of uracil and thymine.
Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "DPYD"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-289 | Recombinant Anti-human DPYD Antibody | ELISA, WB, IF, FuncS | IgG |
| MHH-289 | Recombinant Human Anti-human DPYD Antibody | WB, IP, FuncS | IgG |
| MOB-2088MZ | Recombinant Mouse Anti-Human DPYD Antibody (clone 7D4) | FC, ICC, IF, IHC-P, WB | Mouse antibody |
| VS3-FY1703 | Rabbit Anti-DPYD Recombinant Antibody (clone R02-7C8) | WB, IHC-Fr, IHC-P, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-289-F(E) | Recombinant Anti-human DPYD Antibody Fab Fragment | IF, FC, FuncS | Fab |
| MHH-289-F(E) | Recombinant Human Anti-human DPYD Antibody Fab Fragment | WB, FC, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-289-S(P) | Recombinant Anti-human DPYD Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
| MHH-289-S(P) | Recombinant Human Anti-human DPYD Antibody scFv Fragment | FC, RIA, Biosensors, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1042 | Hi-Affi™ Rabbit Anti-DPYD Recombinant Antibody (clone DS1042AB) | WB, IHC, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY693 | Anti-DPYD Immunohistochemistry Kit | IHC | |
| VS-0525-XY2076 | Anti-Human DPYD Immunohistochemistry Kit | IHC |
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