CytoStream™ Rabbit Anti-DPYD Recombinant Antibody (VS13-YC321) (CAT#: VS13-YC321)

The CytoStream™ Rabbit Anti-DPYD Recombinant Antibody is specific for human DPYD. DPYD is involved in pyrimidine catabolism, impacting drug metabolism, where deficiencies cause metabolic disorders linked to cancer treatment complications. The anti-DPYD antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Formats:
  • Isotype Switching:
  • Fc Engineering:
  • Modalities:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • Recombinant human DPYD.
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human DPYD
  • Species Reactivity
  • Human
  • Applications
  • WB, IHC-P, ICC, IF, FC
  • Conjugate
  • NONE
  • Related Disease
  • Cancer

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Affinity Chromatography purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS (pH 7.4) containing 150 mM NaCl and 50% Glycerol.
  • Preservative
  • 0.02% Sodium azide
  • Storage
  • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Shipping with ice pack.

Applications

  • Application Notes
  • Western blot (WB): 1/500-1/1000
    Immunohistochemistry (IHC): 1/50-1/100
    Immunofluorescence (IF): 1/50-1/200
    Flow cytometry (FC): 1/50-1/100

Target

  • Alternative Names
  • Dihydropyrimidine Dehydrogenase; Dihydrothymine Dehydrogenase; Dihydrouracil Dehydrogenase; EC 1.3.1.2; DHPDHASE; DPD; Dihydropyrimidine Dehydrogenase [NADP(+)]; DHP;
  • Long Name
  • Dihydropyrimidine Dehydrogenase
  • Sequence Similarities
  • Belongs to the dihydropyrimidine dehydrogenase family.
  • Cellular Localization
  • Cytoplasm
  • Function
  • Involved in pyrimidine base degradation.
    Catalyzes the reduction of uracil and thymine.
    Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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