AibGenesis™ Rabbit Anti-DYNLT1 Recombinant Antibody (AibG-Rb-DY384)
CAT#: VS-0426-FY384
Developed through our AI-powered antibody discovery platform, this Rabbit IgG targets DYNLT1 (Tctex-1). Validated for WB, IHC, and IP in multiple species, it offers high-affinity binding for researchers investigating cytoplasmic dynein light chains and their essential role in retrograde organelle transport mechanisms.
Specifications
- Immunogen
- Human
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human DYNLT1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- AibG-Rb-DY384
- Applications
- Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
- Conjugate
- Unconjugated, Biotin and FITC are available.
- Related Disease
- Viral Transport Defect (Rabies)
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Purified
- Format
- Liquid
- Buffer
- 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% Glycerol, 0.05% Protective protein
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- Western Blot (1:500-1:1000), Immunohistochemistry (1:50-1:100), Immunocytochemistry/Immunofluorescence (1:50-1:200), Immunoprecipitation (1:20-1:50)
Target
- Alternative Names
- CW-1; TCTEL1; tctex-1
- Gene ID
- 6993
- UniProt ID
- P63172
- Long Name
- Dynein Light Chain Tctex-Type 1
- Sequence Similarities
- Belongs to the dynein light chain Tctex-type family.
- Cellular Localization
- Cytoplasm, Cytoskeleton, Dynein, Golgi apparatus, Microtubule
- Post Translation Modifications
- Phosphorylated by BMPR2; the phosphorylation is abolished by BMPR2 mutations in exon 12 which lead to truncated forms of BMPR2 and which are linked to primary pulmonary hypertension (PPH1) [MIM:178600].
The phosphorylation status is proposed to regulate the association with the cytoplasmic dynein complex and may have role in cytoplasmic dynein cargo release.
Ubiquitination at Lys56 (NX_P63172 [NX_P63172-1])
Modification sites at PhosphoSitePlus (P63172)
Glycosylation from GlyGen (P63172) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_001278531.1; NP_001278532.1; NP_006510.1
- Function
- Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Binds to transport cargos and is involved in apical cargo transport such as rhodopsin-bearing vesicles in polarized epithelia. May also be a accessory component of axonemal dynein.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "DYNLT1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-FY2091 | Rabbit Anti-DYNLT1 Recombinant Antibody (clone R03-6F2) | WB, IHC-Fr, IHC-P, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY715 | Anti-DYNLT1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2125 | Anti-Mouse DYNLT1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2124 | Anti-Human DYNLT1 Immunohistochemistry Kit | IHC |
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