Mouse Anti-EDA Recombinant Antibody (clone EctoD2); scFv Fragment (CAT#: FAMAB-0124CQ-S(P))
Recombinant Mouse Antibody scFv Fragment clone EctoD2, which is specific to EDA. The blocking antibody EctoD2 can recognize epitopes overlapping the EDA receptor-binding site and efficiently blocked the binding of Fc-EDA1 to EDAR and of Fc-EDA2 to XEDAR in both human and chicken systems. It was capable of completely suppressing the therapeutic effect of Fc-EDA1.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line HEK 293
(Immunofluorescent staining of human cell line HEK 293 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37972/if_selected.jpg
(Immunofluorescent staining of human cell line HEK 293 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37972/if_selected.jpg
Figure 2 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to lipid droplets.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37973/763_F5_2_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to lipid droplets.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37973/763_F5_2_selected.jpg
Figure 3 RNA cell line category: Cell line enhanced (EFO-21, Hep G2, OE19, RPMI-8226)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000158813-EDA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000158813-EDA
Specifications
- Immunogen
- An active recombinant form of EDA1, Fc-EDA1
- Host Species
- Mouse
- Type
- Mouse scFv
- Specificity
- Human EDA
- Species Reactivity
- Human
- Clone
- EctoD2
- Applications
- ELISA, WB, Block
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- EDA; ectodysplasin A; ED1; HED; EDA1; EDA2; HED1; ODT1; XHED; ECTD1; XLHED; ED1-A1; ED1-A2; EDA-A1; EDA-A2; STHAGX1; ectodysplasin-A; oligodontia 1; X-linked anhidroitic ectodermal dysplasia protein
- Gene ID
- 1896
- UniProt ID
- Q92838
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Mouse Antibody Products
IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-269MZ | Mouse Anti-EDA Recombinant Antibody (TAB-269MZ) | ELISA | Mouse IgG |
| TAB-269MZ-S(P) | Mouse Anti-EDA Recombinant Antibody; scFv Fragment (TAB-269MZ-S(P)) | ELISA | Mouse scFv |
| TAB-269MZ-F(E) | Mouse Anti-EDA Recombinant Antibody; Fab Fragment (TAB-269MZ-F(E)) | ELISA | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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