Mouse Anti-F2 Recombinant Antibody (VS-0524-YC44)
CAT#: VS-0524-YC44
The antibody exhibited specific binding affinity for a polypeptide produced during prothrombin activation.
Gene Expression
Normal Tissue
Figure 1 Liver
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/51476/133725_A_8_4.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enriched (Hep G2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000180210-F2
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| Sub Cat | Clone | Applications | Epitope | Size | Conjugation | Endotoxin | Purity | Fc Engineering | |
| VS-0524-YC50 | TA1 | ELISA, WB, SPR | Peptide: DSDRAIEGR | ||||||
| VS-0524-YC45 | POmAb | ELISA, SPR | kringle-1 of prothrombin |
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human prothrombin
- Species Reactivity
- Human
Product Property
- Purification
- Protein G purified
- Purity
- >95%
- Buffer
- PBS, pH 7.4
- Preservative
- No preservative
- Storage
- Centrifuge briefly prior to opening vial. Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western blot: 2 μg/mL
Target
- Alternative Names
- Coagulation Factor II, Thrombin; Prepro-Coagulation Factor II; EC 3.4.21.5; Coagulation Factor II (Thrombin); Coagulation Factor II; Prothrombin B-Chain; Serine Protease
- Gene ID
- 14061
- UniProt ID
- P19221
- Long Name
- prothrombin
- Sequence Similarities
- Belongs to the peptidase S1 family.
- Post Translation Modifications
- The gamma-carboxyglutamyl residues, which bind calcium ions, result from the carboxylation of glutamyl residues by a microsomal enzyme, the vitamin K-dependent carboxylase. The modified residues are necessary for the calcium-dependent interaction with a negatively charged phospholipid surface, which is essential for the conversion of prothrombin to thrombin.
- Protein Refseq
- NP_034298.1
- Function
- Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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