Rabbit Anti-FCER2 Recombinant Antibody (clone R08-8A1)
CAT#: VS3-XY3355
This product is a rabbit recombinant antibody specific for human FCER2 (Fc epsilon receptor II), which has essential roles in the regulation of IgE production and in the differentiation of B cells. It specifically recognizes and binds to human FCER2. It has been used in a variety of applications, such as Western Blot, Immunohistochemistry-Paraffin and Flow cytometry.
Gene Expression
Normal Tissue
Figure 1 High expression in lymph node
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8928/24032_A_9_8_val_selected.jpg
Normal Tissue
Figure 2 Low expression in endometrium 1
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8928/24032_B_4_3_val_selected.jpg
Normal Tissue
Figure 3 Bone marrow
Hematopoietic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2624/6435_B_5_4.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2624/6435_A_9_8.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enriched (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000104921-FCER2
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human FCER2
- Species Reactivity
- Human
- Clone
- R08-8A1
- Applications
- WB, IHC-P, FC
- Related Disease
- Chronic Conjunctivitis; Extrinsic Allergic Alveolitis
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
FC: 1/50-1/100
Target
- Alternative Names
- CD23; FCE2; CD23A; IGEBF; CLEC4J; FCErII; BLAST-2
- Gene ID
- 2208
- UniProt ID
- P06734
- Long Name
- Fc epsilon receptor II
- Cellular Localization
- Cell membrane, Membrane, Secreted
- Post Translation Modifications
- N- and O-glycosylated.
The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding.
- Protein Refseq
- NP_001193948.2; NP_001207429.1; NP_001993.2
- Function
- Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
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Secondary Antibody
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| NEUT-786CQ | Mouse Anti-FCER2 Recombinant Antibody (clone CBL016) | Neut, FC, WB | Mouse IgG2 |
| NEUT-788CQ | Mouse Anti-FCER2 Recombinant Antibody (clone MM0164-2C23) | WB, Neut, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-787CQ | Mouse Anti-FCER2 Recombinant Antibody (clone TU1) | FC, IHC-Fr, ICC, WB, Block | Mouse IgG3, κ |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1268 | Hi-Affi™ Rabbit Anti-FCER2 Recombinant Antibody (clone DS1268AB) | IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1148-FY-F(E) | Human Anti-FCER2 Recombinant Antibody; Fab Fragment (HPAB-1148-FY-F(E)) | Activ | Human Fab |
| HPAB-1149-FY-F(E) | Monkey Anti-FCER2 Recombinant Antibody; Fab Fragment (HPAB-1149-FY-F(E)) | Activ | Monkey Fab |
| HPAB-0530-YJ-S(P) | Mouse Anti-FCER2 Recombinant Antibody (clone 1E9); scFv Fragment | ELISA, IHC | Mouse scFv |
| HPAB-0531-YJ-S(P) | Human Anti-FCER2 Recombinant Antibody (clone ch1E9); scFv Fragment | ELISA, IHC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1148-FY-S(P) | Monkey Anti-FCER2 Recombinant Antibody; scFv Fragment (HPAB-1148-FY-S(P)) | Activ | Monkey scFv |
| HPAB-1149-FY-S(P) | Monkey Anti-FCER2 Recombinant Antibody; scFv Fragment (HPAB-1149-FY-S(P)) | Activ | Monkey scFv |
| HPAB-0530-YJ-F(E) | Mouse Anti-FCER2 Recombinant Antibody (clone 1E9); Fab Fragment | ELISA, IHC | Mouse Fab |
| HPAB-0531-YJ-F(E) | Human Anti-FCER2 Recombinant Antibody (clone ch1E9); Fab Fragment | ELISA, IHC | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| VS13-YC385 | CytoStream™ Rabbit Anti-FCER2 Recombinant Antibody (VS13-YC385) | IHC-P, ICC, IF, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY83 | Human Anti-FCER2 (clone 1E9) scFv-Fc Chimera | ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC203 | Recombinant Anti-FCER2 Vesicular Antibody, EV Displayed (VS-0425-YC203) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2478 | Anti-FCER2 Immunohistochemistry Kit | IHC |
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