Rabbit Anti-GAP43 Recombinant Antibody (VS3-CJ722) (CAT#: VS3-CJ722)

• Immunogen
• Recombinant protein

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human, Mouse, Rat GAP43

• Species Reactivity
• Human, Mouse, Rat

• Applications
• WB, ICC, IF, IHC, IP, FC

• Conjugate
• Unconjugated

• Purification
• Protein A affinity purified

• Purity
• >95% as determined by SDS-PAGE

• Format
• Liquid

• Buffer
• 40% Glycerol, 1% BSA, TBS, pH7.4.

• Preservative
• 0.05% Sodium Azide

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• This antibody has been tested for use in Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Flow Cytometry.

• Alternative Names
• B-50; PP46; GAP-43

• Gene ID
• 2596

• UniProt ID
• P17677

• Sequence Similarities
• Belongs to the neuromodulin family.

• Cellular Localization
• Cell membrane, Cell projection, Cytoplasm, Membrane, Synapse

• Post Translation Modifications
• Phosphorylated (By similarity).
  Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity (By similarity).
  Palmitoylated by ZDHHC3 (By similarity).
  Palmitoylation is regulated by ARF6 and is essential for plasma membrane association and axonal and dendritic filopodia induction (PubMed:14978216).
  Deacylated by LYPLA2 (PubMed:21152083).

• Protein Refseq
• NP_001123536.1; NP_002036.1

• Function
• This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Secondary Antibody

• 2ND-057CQ
• Donkey Anti-Rabbit IgG (H&L) Antibody

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

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