Rabbit Anti-GCG Recombinant Antibody (clone R04-8D3)
CAT#: VS3-XY3366
The antibody is a recombinant rabbit antibody targeting the GCG (Glucagon), which regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. It specifically reacts with human GCG. It has been determined using Western Blot, Immunohistochemistry-Paraffin, Immunocytochemistry or Immunofluorescence.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36760/1675_C6_32_selected.jpg
Normal Tissue
Figure 2 High expression in pancreas
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36760/123313_A_2_3_val_selected.jpg
Normal Tissue
Figure 3 Low expression in liver
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36760/123313_A_9_4_val_selected.jpg
Normal Tissue
Figure 4 Pancreas
Pancreatic endocrine cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40/255_A_2_3.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (EFO-21, U-2 OS, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000115263-GCG
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human GCG
- Species Reactivity
- Human
- Clone
- R04-8D3
- Applications
- WB, IHC-P, ICC, IF
- Related Disease
- Dumping Syndrome; Hyperglycemia
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IF: 1/50-1/200
Target
- Alternative Names
- GLP1; GLP2; GRPP; GLP-1
- Gene ID
- 2641
- UniProt ID
- P01275
- Long Name
- Glucagon
- Cellular Localization
- Secreted
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (P01275)
Modification sites at neXtProt (NX_P01275)
- Protein Refseq
- NP_002045.1
- Function
- [Glucagon]: Plays a key role in glucose metabolism and homeostasis.
Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis.
A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia.
Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "GCG"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0117MZ | Recombinant Mouse Anti-Glucagon-Like Peptide (GLP1) Antibody (clone JD/GLP-3/20) | ICC, IHC-P | Mouse antibody |
| ZG-0382J | Mouse Anti-GCG Recombinant Antibody (ZG-0382J) | WB, ELISA | Mouse IgG |
| VS3-CJ252 | Mouse Anti-GCG Recombinant Antibody (VS3-CJ252) | IHC | Mouse IgG2b |
| VS3-CJ253 | Mouse Anti-GCG Recombinant Antibody (VS3-CJ253) | IHC | Mouse IgG1 |
| VS3-XY766 | Mouse Anti-GCG Recombinant Antibody (clone 329CT36.10.10) | WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1415 | Hi-Affi™ Rabbit Anti-GCG Recombinant Antibody (clone DS1415AB) | WB | Rabbit IgG |
| MOR-4579 | Hi-Affi™ Rabbit Anti-GCG Recombinant Antibody (clone TH91DS) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0352-CN-S(P) | Human Anti-GCG Recombinant Antibody (HPAB-0352-CN-S(P)); scFv Fragment | ELISA, FC, RIA | Human scFv |
| HPAB-0353-CN-S(P) | Human Anti-GCG Recombinant Antibody (HPAB-0353-CN-S(P)); scFv Fragment | ELISA, FC, RIA | Human scFv |
| HPAB-0354-CN-S(P) | Human Anti-GCG Recombinant Antibody (HPAB-0354-CN-S(P)); scFv Fragment | ELISA, FC, RIA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0352-CN-F(E) | Human Anti-GCG Recombinant Antibody (HPAB-0352-CN-F(E)); Fab Fragment | ELISA, FC, RIA | Human Fab |
| HPAB-0353-CN-F(E) | Human Anti-GCG Recombinant Antibody (HPAB-0353-CN-F(E)); Fab Fragment | ELISA, FC, RIA | Human Fab |
| HPAB-0354-CN-F(E) | Human Anti-GCG Recombinant Antibody (HPAB-0354-CN-F(E)); Fab Fragment | ELISA, FC, RIA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-032CN | Human Anti-GCG Recombinant Antibody (NS-032CN) | ELISA | Human IgG2 |
| NS-032CN-F(E) | Human Anti-GCG Recombinant Antibody; Fab Fragment (NS-032CN-F(E)) | ELISA | Human Fab |
| NS-032CN-S(P) | Human Anti-GCG Recombinant Antibody; scFv Fragment (NS-032CN-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0662-CN | Mouse Anti-GCG Recombinant Antibody (clone 5F1) | WB, IHC, IF, FC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-XY27 | Mouse Anti-GCG Agonistic Antibody (VS-0724-XY27) | WB, Agonistic assays | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2760 | Anti-GCG Immunohistochemistry Kit | IHC | |
| VS-0525-XY2761 | Anti-Mouse GCG Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC128 | Recombinant Anti-GCG Eliminating Antibody, pH-Sensitive (VS-0625-YC128) | Antigen-Sweeping In Vivo. | Human IgG4 |
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