How does this antibody facilitate research into platelet glycoprotein VI?

We have developed this human recombinant antibody to target GP6 with high specificity, ensuring accurate detection in ELISA. The antibody is manufactured with strict quality control, achieving>95% purity, which supports its effective use in studies related to platelet function and glycoprotein characterization.

What benefits does the product offer for in vitro platelet research?

Our antibody offers reliable binding to human GP6 with an excellent purity profile. Designed for in vitro assays such as ELISA assays, its robust performance and comprehensive product information ensure reproducible data for research into platelet signal transduction and receptor mapping.

Human Anti-GP6 Recombinant Antibody (clone F1232-18-3)

CAT#: HPAB-1715-FY

This product is a recombinant antibody that recognizes GP6. The monoclonal antibody F1232-18-3 reacts with the epitope of GP6.

Published Data Gene Expression

Inhib

Figure 1 Shows the inhibition of binding between GPVI and collagen by the chimeric antibody and the mouse hybridoma antibody.

Inhib

Figure 2 Shows the inhibition of binding between GPVI and collagen by the chimeric antibody and the mouse hybridoma antibody.

ELISA

Figure 3 Shows the results of reactivity for mouse hybridoma antibody and chimeric antibody.

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Subcellular Location Figure 1 IF staining of human cell line HEL

Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/47611/1925_A11_24_cr5cd55a323d93f_selected.jpg

Normal Tissue Figure 2 IHC staining of human bone marrow

Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in megakaryocytes.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/66482/ihc_selected.jpg

Normal Tissue Figure 3 Cerebral cortex

Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/66482/149862_B_9_5.jpg

Normal Tissue Figure 4 Colon

Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/66482/149862_A_7_3.jpg

Normal Tissue Figure 5 Kidney

Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/66482/149862_A_8_5.jpg

Normal Tissue Figure 6 Testis

Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: Low Intensity: Weak Quantity: 75%-25% Spermatogonia cells Staining: Low Intensity: Moderate

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/66482/149862_A_6_6.jpg

RNA Expression Figure 7 RNA cell line category: Group enriched (HEL, K-562, U-2 OS)

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000088053-GP6

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Specifications

Immunogen
Human platelet membrane glycoprotein VI (GPVI).

Host Species
Human

Type
Human IgG

Specificity
Human GP6

Species Reactivity
Human

Clone
F1232-18-3

Applications
ELISA

Product Property

Purity
>95% as determined by SDS-PAGE and HPLC analysis

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

Application Notes
The GP6 antibody has been reported in applications of Inhibition, Enzyme-linked Immunosorbent Assay.

Target

Alternative Names
Glycoprotein VI Platelet; Platelet Glycoprotein VI; Glycoprotein 6; GPVI; Glycoprotein VI (Platelet); Platelet Collagen Receptor; BDPLT11; GPIV

Gene ID
51206

UniProt ID
Q9HCN6

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Breast cancer biomarkers at key points during disease progression

Excellent for Platelet Studies

The Human Anti-GP6 recombinant antibody (clone F1232-18-3) is excellent for research on platelet glycoprotein VI. Its high purity and clear documentation on purification and storage have provided consistent results in ELISA. I value the robust performance and detailed technical insights provided for platelet-focused experiments.

Consistently Reliable

I have been very satisfied with the performance of this anti-GP6 antibody. Its high purity (>95% by SDS-PAGE) and effective binding properties make it a reliable reagent in my immunoassays for platelet research. The detailed product instructions and quality control data add to its dependability and usability in diverse research applications.

Q&As

How does this antibody facilitate research into platelet glycoprotein VI?

A: We have developed this human recombinant antibody to target GP6 with high specificity, ensuring accurate detection in ELISA. The antibody is manufactured with strict quality control, achieving>95% purity, which supports its effective use in studies related to platelet function and glycoprotein characterization.
What benefits does the product offer for in vitro platelet research?

A: Our antibody offers reliable binding to human GP6 with an excellent purity profile. Designed for in vitro assays such as ELISA assays, its robust performance and comprehensive product information ensure reproducible data for research into platelet signal transduction and receptor mapping.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-1715-FY.pdf

MSDS

MSDS - HPAB-1715-FY.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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CAT
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