AibGenesis™ Rabbit Anti-GRK3 Recombinant Antibody (AibG-Rb-GR452)
CAT#: VS-0426-FY452
Developed through our AI-powered antibody discovery platform, this Rabbit IgG targets GRK3. Validated for WB, IHC, and IF in Human samples, it offers high specificity for studying the phosphorylation-dependent regulation of sensory receptors and its implications in neurological and inflammatory disease models.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/804/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human pancreas
Immunohistochemical staining of human pancreas shows strong nuclear positivity in exocrine glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/804/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Nuclear Glial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/804/1594_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/804/1594_A_8_3.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/804/1594_A_4_6.jpg
Normal Tissue
Figure 6 Lymph node
Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/804/1594_A_7_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (HDLM-2, JURKAT)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100077-GRK3
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Specifications
- Immunogen
- Human
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human GRK3
- Species Reactivity
- Human
- Clone
- AibG-Rb-GR452
- Applications
- Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence
- Conjugate
- Unconjugated, Biotin and FITC are available.
- Related Disease
- Chronic Heart Failure
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Format
- Liquid
- Buffer
- PBS, pH 7.4, 150 mM NaCl, 50% Glycerol
- Preservative
- 0.02% New type preservative N
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- Western Blot (1:1000-1:5000), Immunohistochemistry (1:200-1:500), Immunocytochemistry/Immunofluorescence (1:20-1:50)
Target
- Alternative Names
- ADRBK2; BARK2; GRK3
- Gene ID
- 157
- UniProt ID
- P35626
- Long Name
- G Protein-Coupled Receptor Kinase 3
- Function
- A G-protein coupled receptor kinase; it specifically phosphorylates activated receptors to trigger desensitization and internalization, particularly in olfactory and chemokine signaling.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "GRK3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0094 | Rabbit Anti-GRK3 Recombinant Antibody (clone DS94AB) | ICC, IF, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2929 | Anti-GRK3 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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