AibGenesis™ Rabbit Anti-GYPC Recombinant Antibody (AibG-Rb-YP179)
CAT#: VS14-YC380
Optimized via neural network modeling, the anti-GYPC mAb (AibG-Rb-YP179) ensures precise recognition of the human GYPC protein. GYPC (Glycophorin C) is an integral membrane glycoprotein that regulates the mechanical stability of the red cell membrane by anchoring the cytoskeleton to the lipid bilayer. It serves as a structural scaffold that modulates integrin and cell-adhesion signaling in various hematopoietic tissues.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8965/1849_G2_33_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line K-562
Immunofluorescent staining of human cell line K-562 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8965/2054_F5_3_blue_red_green.jpg
Subcellular Location
Figure 3 IF staining of human cell line SK-MEL-30
Immunofluorescent staining of human cell line SK-MEL-30 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8965/1803_F4_1_blue_red_green.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8965/24719_B_9_5.jpg
Normal Tissue
Figure 5 Colon
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8965/24657_A_7_3.jpg
Normal Tissue
Figure 6 Testis
Spermatogonia cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8965/24657_A_6_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8965/24657_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (HHSteC, K-562, SK-MEL-30, U-266/70)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136732-GYPC
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- GYPC
- Species Reactivity
- Human
- Clone
- AibG-Rb-YP179
- Applications
- Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC)
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% Glycerol
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- Western Blot (WB): 1/500-1/2000
Immunohistochemistry (IHC): 1/50-1/200
Immunocytochemistry (ICC): 1/50-1/200
Immunofluorescence (IF): 1/50-1/200
Immunoprecipitation (IP): 1/50
Flow Cytometry (FC): 1/50
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "GYPC"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1336z | Mouse Anti-GYPC Recombinant Antibody (clone 23B5) | WB, IHC, IP | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1735MZ | Recombinant Mouse Anti-Human GYPC Antibody (clone CSJD20) | FC, WB | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1549 | Rabbit Anti-GYPC Recombinant Antibody (clone DS1549AB) | FC, ICC, IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS2-QX39 | Mouse Anti-GYPC Recombinant Antibody (clone BGRL 100) | IB, IP, ICC | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS2-QX40 | Mouse Anti-GYPC Recombinant Antibody (clone BRIC 10) | IB | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS2-QX41 | Mouse Anti-GYPC Recombinant Antibody (clone BRIC 4) | ICC, IF, WB | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1189 | AbPlus™ Anti-GYPC Magnetic Beads (VS-0724-YC1189) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC748 | Recombinant Anti-GYPC Vesicular Antibody, EV Displayed (VS-0425-YC748) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2997 | Anti-GYPC Immunohistochemistry Kit | IHC |
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