Mouse Anti-HDAC6 Recombinant Antibody (clone 4G6F9)
CAT#: VS7-0425-WR28
This product is a mouse IgG2b recombinant antibody that binds to human HDAC6. 4G6F9 recognizes the specific domains AA: 482-800 on human HDAC6. This antibody can be used for FC assay.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26321/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4236/12458_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4236/12458_A_7_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4236/12458_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Round or early spermatids Staining: Medium Intensity: Moderate Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4236/12458_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000094631-HDAC6
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Specifications
- Immunogen
- Recombinant human HDAC6 (AA: 482-800) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Human HDAC6
- Species Reactivity
- Human
- Clone
- 4G6F9
- Molecule Class
- Enzyme
- Applications
- FC
- Conjugate
- Unconjugated
- Related Disease
- Cancer; Neurodegenerative Diseases; Inflammatory Diseases; Charcot-Marie-Tooth disease (CMT); Viral Infections; Sepsis
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- HD6; JM21; CPBHM; KDAC6; PPP1R90
- Gene ID
- 10013
- UniProt ID
- Q9UBN7
- Long Name
- Histone deacetylase 6
- Cellular Localization
- Cell projection; Cytoplasm; Cytoskeleton; Nucleus
- Post Translation Modifications
- Methylation; Phosphoprotein; Ubl conjugation
- Protein Refseq
- NP_001308154.1
- Function
- Actin-binding; Chromatin regulator; Hydrolase; Repressor
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Related Diseases
Alcoholism
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
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- Product Name
Secondary Antibody
- CAT
- Product Name
Reconstitution Buffer
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "HDAC6"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1577 | Rabbit Anti-HDAC6 Recombinant Antibody (clone DS1577AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-0097C | Mouse Anti-HDAC6 Recombinant Antibody (clone ABT-HDAC6) | IHC-P, IF | Mouse IgG |
| ZG-0712J | Rabbit Anti-HDAC6 Recombinant Antibody (clone 2H12) | ELISA, WB, IHC, IP | Rabbit IgG |
| VS3-QX508 | Mouse Anti-HDAC6 Recombinant Antibody (clone 3B2-F5-G6) | WB | Mouse IgG2a |
| VS3-WK1186 | Mouse Anti-HDAC6 Recombinant Antibody (VS3-WK1186) | IHC | Mouse IgG1 |
| VS3-WK1187 | Rabbit Anti-HDAC6 Recombinant Antibody (VS3-WK1187) | WB, ICC, IF, IHC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY241 | Mouse Anti-NHP HDAC6 Recombinant Antibody (clone OTI4C5) | WB, IHC, IF, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1004 | Anti-HDAC6 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3101 | Anti-Human HDAC6 Immunohistochemistry Kit | IHC |
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