Human Anti-HIV-1 Env Recombinant Antibody (clone 8.9D) (CAT#: MRO-2744CQ)
This product is a recombinant human anti-HIV-1 monoclonal antibody. 8.9D specifically binds to HIV-1 Env.
Specific Inquiry
Neu
Figure 1 MAb neutralization of Env 6.3 and V1 mutants.
Zero-month FPL Env 6.3 was used as a backbone for mutations at residues 134 and 132, and these Envs were assessed for sensitivity to MAbs 8.9D, 6.4C, and 13.6A using pseudoviruses.
Lynch, R. M., Rong, R., Boliar, S., Sethi, A., Li, B., Mulenga, J., ... & Derdeyn, C. A. (2011). The B cell response is redundant and highly focused on V1V2 during early subtype C infection in a Zambian seroconverter. Journal of virology, 85(2), 905-915.
Neu
Figure 2 MAb neutralization of Env 6.3 and V2 mutants.
Zero-month FPL Env 6.3 was used as a backbone for mutations at residue 189 in conjunction with residue 134, and these Envs were assessed for sensitivity to MAbs 8.9D, 6.4C, and 13.6A using pseudoviruses.
Lynch, R. M., Rong, R., Boliar, S., Sethi, A., Li, B., Mulenga, J., ... & Derdeyn, C. A. (2011). The B cell response is redundant and highly focused on V1V2 during early subtype C infection in a Zambian seroconverter. Journal of virology, 85(2), 905-915.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Recognizes HIV-1 Env
- Species Reactivity
- HIV-1
- Clone
- 8.9D
- Applications
- ELISA, Neut
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 Env antibody has been reported in applications of Neutralization.
Target
- Alternative Names
- ENV; gp160; envelope glycoprotein; Envelope surface glycoprotein gp160; precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone 8.9D"
See other products for "HIV-1 Env"
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-474-S(P) | Recombinant Anti-HIV-1 Env Antibody scFv Fragment | WB, ELISA, IHC, FuncS | scFv |
| PSBC-420 | Human Anti-HIV-1 Env Recombinant Antibody (clone CAP228-3D); scFv Fragment | Neut | Human scFv |
| HPAB-2324LY-S(P) | Mouse Anti-HIV-1 Env Recombinant Antibody; scFv Fragment (HPAB-2324LY-S(P)) | Neut, ELISA | Mouse scFv |
| HPAB-2325LY-S(P) | Mouse Anti-HIV-1 Env Recombinant Antibody; scFv Fragment (HPAB-2325LY-S(P)) | Neut, ELISA | Mouse scFv |
| HPAB-2326LY-S(P) | Mouse Anti-HIV-1 Env Recombinant Antibody; scFv Fragment (HPAB-2326LY-S(P)) | Neut, ELISA | Mouse scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-057 | Recombinant Anti-HIV-1 env VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-474-F(E) | Recombinant Human Anti-HIV-1 Env Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
| PFBL-137 | Human Anti-HIV-1 Env Recombinant Antibody (clone PGT124); Fab Fragment | WB, Neut, FuncS | Human Fab |
| PFBL-141 | Human Anti-HIV-1 Env Recombinant Antibody (clone 35O22); Fab Fragment | WB, ELISA, Neut, FuncS | Human Fab |
| PFBL-143 | Human Anti-HIV-1 Env Recombinant Antibody (clone 9H+3L); Fab Fragment | WB, ELISA, IF, FuncS | Human Fab |
| PFBL-144 | Human Anti-HIV-1 Env Recombinant Antibody (clone C11); Fab Fragment | WB, ELISA, FuncS | Human Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-379 | Human Anti-HIV-1 Env Recombinant Antibody (clone VRC0) | Neut, FuncS | Human IgG |
| PABL-514 | Human Anti-HIV-1 Env Recombinant Antibody (clone 17B) | FC, Neut | Human IgG1 |
| PABL-516 | Monkey Anti-HIV-1 Env Recombinant Antibody (clone GE356) | WB, ELISA, FuncS | Monkey IgG |
| PABL-519 | Human Anti-HIV-1 Env Recombinant Antibody (PABL-519) | Neut | Human IgG |
| MRO-2796CQ | Human Anti-HIV-1 Env Recombinant Antibody (clone 3D5) | Neut | Human IgG |
MHC Tetramer for Virology
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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