Mouse Anti-HIV-1 gp160 Recombinant Antibody (clone 2D3 (419 2D3)) (CAT#: MRO-3829CQ)
Recombinant mouse antibody to gp160(419-439). 2D3 also binds to native but not denatured gp120.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Inhib
Figure 1 MAbs 11A8 and 2D3 compete for binding to gp120.
Binding to gp120 of biotinylated 2D3 in the presence of unconjugated MAbs 2D3 or 11A8 was evaluated in ELISA.
Kelker, H. C., Itri, V. R., & Valentine, F. T. (2010). A strategy for eliciting antibodies against cryptic, conserved, conformationally dependent epitopes of HIV envelope glycoprotein. PLoS One, 5(1).
ELISA
Figure 2 Antibodies elicited by MCPs fail to recognize denatured gp120.
All sera and MAb preparations were diluted as indicated in the Figure.
Kelker, H. C., Itri, V. R., & Valentine, F. T. (2010). A strategy for eliciting antibodies against cryptic, conserved, conformationally dependent epitopes of HIV envelope glycoprotein. PLoS One, 5(1).
FC
Figure 3 A MAb elicited by 426 MCP (11A8) recognizes HIV-1 on the surface of infected cells.
Antibody binding was detected using PE conjugated secondary antibody and measured by flow cytometry. Flow histogram plots are displayed.
Kelker, H. C., Itri, V. R., & Valentine, F. T. (2010). A strategy for eliciting antibodies against cryptic, conserved, conformationally dependent epitopes of HIV envelope glycoprotein. PLoS One, 5(1).
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Recognizes HIV-1 gp160(419-439)
- Species Reactivity
- HIV-1
- Clone
- 2D3 (419 2D3)
- Applications
- ELISA, FC, Inhib
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 gp160 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Flow Cytometry, Inhibition. ELISA: Protein concentration of the stock of undiluted MAb preparations used was, respectively: 1.96 mg/ml (MAb 11A8), and 0.5 mg/ml (MAb 2D3).
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 2D3 (419 2D3)"
See other products for "HIV-1 gp160"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
ScFv Antibody Products
Human Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-382 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08) | Neut, FuncS | Human IgG, κ |
| PABL-554 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone C38-VRC16.01) | FC, Neut | Human IgG |
| PABL-555 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone C38-VRC18.02) | FC, Neut | Human IgG |
| PABL-556 | Human Anti-HIV-1 gp160 Recombinant Antibody (PABL-556) | Neut | Human IgG |
| PABL-557 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone Z258-VRC27.01) | FC, Neut | Human IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for MRO-3829CQ. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: IHC, ELISA, FC, WB, ADCC, FuncS
Application: WB, ELISA, FC, IHC, IP
-YJ5.png)
Application: WB, ELISA, FC, IHC, IP
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, FuncS, RIA, IP, IF, IHC, IA, Block
For Research Use Only. Not For Clinical Use.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
