Human Anti-HLA-B27 Recombinant Antibody (clone HD6); scFv Fragment (CAT#: HPAB-J0122-YC-S(P))
Provided is an antibody, which binds to HLA-B27 heavy-chain homodimers, termed HC-B27, HLA-B272 or B272, particularly recognizing B272 homodimers and which does not recognize or bind HLA-B27 heterotrimers (B27) including HLA-B27 heterotrimers with β2 microglobulin and peptide. It has shown that HD6 bound to recombinant B272 complexes but not to HLA-A2, B7 or B27 complexes in ELISA. HD6 inhibited binding of B272 to KIR3DL1, KIR3DL2 and LILRB2 immunoreceptors and B272-mediated survival and proliferation of human NK cells expressing KIR3DL2.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Host Species
- Human
- Type
- Human scFv
- Specificity
- Human HLA-B27
- Species Reactivity
- Human
- Clone
- HD6
- Applications
- ELISA, FC
- Related Disease
- ankylosing spondylitis (AS) and reactive arthritis (ReA or Reiter's syndrome)
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Human leukocyte antigen (HLA) B27; B*2701-2759
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone HD6"
See other products for "HLA-B27"
Select a product category from the dropdown menu below to view related products.
Please select product type
Mouse Antibodies
IgG Antibodies
ScFv Antibodies
Fab Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-093CT | Human Anti-HLA-B27 Recombinant Antibody (TAB-093CT) | ELISA, Neut, FC | Human IgG |
| TAB-093CT-S(P) | Human Anti-HLA-B27 Recombinant Antibody; scFv Fragment (TAB-093CT-S(P)) | ELISA, Neut, FC | Human scFv |
| TAB-093CT-F(E) | Human Anti-HLA-B27 Recombinant Antibody; Fab Fragment (TAB-093CT-F(E)) | ELISA, Neut, FC | Human Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-J0122-YC-S(P). Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: WB, ELISA, IP, FC, FuncS, Neut, IF
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: WB, Neut, ELISA, IF, IP, FuncS, FC
-2.png)
Application: WB, ELISA
-2-1.png)
Application: ELISA
Application: ELISA, IHC, FC, IP, IF, FuncS
-3.jpg)
Application: Neut
Application: WB, FC, IF, Inhib, ELISA, IHC
For Research Use Only. Not For Clinical Use.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
