Human Anti-IAV NA Recombinant Antibody (clone 3H03)

CAT#: VS-0326-FY152

This is a human-derived monoclonal IgG1 antibody that specifically targets a highly conserved, previously uncharacterized epitope located on the lateral surface of the influenza N1 neuraminidase. In contrast to antibodies that bind to the enzyme's active site, this antibody confers remarkably broad protective efficacy spanning nearly nine decades of seasonal H1N1 variants, as well as zoonotic avian strains (such as H5N1 and H7N1) and swine N1 lineages. Its unique binding profile enables exceptional cross-strain coverage, offering a promising strategy for combating diverse influenza N1 threats.

Specifications

  • Immunogen
  • Natural infection with Pandemic H1N1 (A/California/04/2009-like) virus.
  • Host Species
  • Human
  • Type
  • Human IgG1
  • Antibody Isotype
  • IgG1
  • Specificity
  • Broad N1 reactivity: Seasonal H1N1 (1934-2019), Eurasian avian-swine H1N1, Avian H5N1, and Avian H7N1. (No cross-reactivity with N2 or N4).
  • Species Reactivity
  • Influenza Virus A (IAV)
  • Clone
  • 3H03
  • Applications
  • Enzyme-linked Immunosorbent Assay, Neutralization, Antibody-Dependent Cellular Cytotoxicity
  • Related Disease
  • Influenza A

Product Property

  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Flu A NA
  • Long Name
  • Influenza A Virus Neuraminidase
  • Function
  • Neuraminidase; cleaves sialic acids to release progeny flu viruses from host cells.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

Certificate of Analysis Lookup

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Secondary Antibody

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