AbPlus™ Anti-IGFBP7 Magnetic Beads (VS-0724-YC943) (CAT#: VS-0724-YC943)
The AbPlus Anti-IGFBP7 Magnetic Beads (VS-0724-YC943) is an innovative affinity resin which is bound with anti-IGFBP7 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of IGFBP7 protein under native and denaturing conditions.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20668/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20668/if_selected.jpg

Figure 2 IHC staining of human kidney
(Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/ihc_selected.jpg
(Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/ihc_selected.jpg

Figure 3 IHC staining of human pancreas
(Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in islet cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20668/ihc_selected.jpg
(Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in islet cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20668/ihc_selected.jpg

Figure 4 Cerebral cortex
(Neuronal cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_B_7_5.jpg
(Neuronal cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_B_7_5.jpg

Figure 5 Colon
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_3.jpg
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_3.jpg

Figure 6 Liver
(Hepatocytes
Staining: Not detected
Intensity:Weak
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_4.jpg
(Hepatocytes
Staining: Not detected
Intensity:Weak
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_4.jpg

Figure 7 Testis
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_5_6.jpg
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_5_6.jpg

Figure 8 Lymph node
(Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_8.jpg
(Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_8.jpg

Figure 9 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, hTERT-RPE1, RPTEC TERT1, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163453-IGFBP7
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163453-IGFBP7
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-IGFBP7 specific antibody
- Target
- IGFBP7
- Immunogen
- Recombinant human IGFBP7, aa 1-282.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]
- Alternative Names
- Insulin Like Growth Factor Binding Protein 7
- Gene ID
- 3490
- UniProt ID
- Q16270
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-546 | Recombinant Anti-human IGFBP7 Antibody | ELISA, WB, IF, FuncS | IgG |
HPAB-0134-CN | Mouse Anti-IGFBP7 Recombinant Antibody (HPAB-0134-CN) | ELISA | Mouse IgG1, κ |
VS3-WK50 | Mouse Anti-IGFBP7 Recombinant Antibody (clone E7-D9) | WB, ELISA | Mouse IgG1 |
VS3-FY741 | Recombinant Rabbit Anti-IGFBP7 Antibody (clone R04-5D9) | WB, IHC-Fr, IHC-P, ICC, IF | Rabbit IgG |
VS-0723-WK137 | Human Anti-IGFBP7 Recombinant Antibody (VS-0723-WK137) | FC | Chimeric (rabbit/human) IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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