Recombinant Human Anti-human IGFBP7 Antibody
CAT#: MHH-546
Recombinant Human Antibody is specific to Human IGFBP7, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-IGFBP7 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-IGFBP7 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20668/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human kidney
Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/ihc_selected.jpg
Normal Tissue
Figure 3 IHC staining of human pancreas
Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in islet cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20668/ihc_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Neuronal cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_B_7_5.jpg
Normal Tissue
Figure 5 Colon
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_3.jpg
Normal Tissue
Figure 6 Liver
Hepatocytes
Staining: Not detected
Intensity:Weak
Quantity: <25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_4.jpg
Normal Tissue
Figure 7 Testis
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_5_6.jpg
Normal Tissue
Figure 8 Lymph node
Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, hTERT-RPE1, RPTEC TERT1, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163453-IGFBP7
❮
❯
Specifications
- Immunogen
- Human insulin-like growth factor binding protein 7
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Antibody Isotype
- IgG1
- Specificity
- Tested positive against native Human insulin-like growth factor binding protein 7
- Species Reactivity
- Human
- Applications
- Formats of immunological tests: Western blot; Immunohistochemistry; Functional Study
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.
Target
- Alternative Names
- IGFBP7; insulin-like growth factor binding protein 7; AGM; PSF; TAF; FSTL2; IBP-7; MAC25; IGFBP-7; RAMSVPS; IGFBP-7v; IGFBPRP1; insulin-like growth factor-binding protein 7; IGFBP-rP1; angiomodulin; IGF-binding protein 7; PGI2-stimulating factor; tumor-de
- Gene ID
- 3490
- UniProt ID
- Q16270
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "IGFBP7"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-546-F(E) | Recombinant Anti-human IGFBP7 Antibody Fab Fragment | WB, FACS, FuncS | Fab |
| MHH-546-F(E) | Recombinant Human Anti-human IGFBP7 Antibody Fab Fragment | ELISA, Nert, FuncS | Fab |
| HPAB-0134-CN-F(E) | Mouse Anti-IGFBP7 Recombinant Antibody; Fab Fragment (HPAB-0134-CN-F(E)) | ELISA | Mouse Fab |
| HPAB-0135-CN-F(E) | Mouse Anti-IGFBP7 Recombinant Antibody; Fab Fragment (HPAB-0135-CN-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-546-S(P) | Recombinant Anti-human IGFBP7 Antibody scFv Fragment | WB, ELISA, IHC, FuncS | scFv |
| MHH-546-S(P) | Recombinant Human Anti-human IGFBP7 Antibody scFv Fragment | ELISA, WB, FC, FuncS | scFv |
| HPAB-0134-CN-S(P) | Mouse Anti-IGFBP7 Recombinant Antibody; scFv Fragment (HPAB-0134-CN-S(P)) | ELISA | Mouse scFv |
| HPAB-0135-CN-S(P) | Mouse Anti-IGFBP7 Recombinant Antibody; scFv Fragment (HPAB-0135-CN-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-097ZJ | Llama Anti-IGFBP7 Recombinant Antibody (TAB-097ZJ) | IHC, ELISA | Llama VHH |
| TAB-098ZJ | Llama Anti-IGFBP7 Recombinant Antibody (TAB-098ZJ) | ELISA, IHC, IF, FuncS | Llama VHH |
| HPAB-AP908-YC | Recombinant Lama glama Anti-IGFBP7 Single Domain Antibody (HPAB-AP908-YC) | FuncS | Lama glama VHH |
| HPAB-AP909-YC | Recombinant Lama glama Anti-IGFBP7 Single Domain Antibody (HPAB-AP909-YC) | FuncS | Lama glama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1762 | Rabbit Anti-IGFBP7 Recombinant Antibody (clone DS1762AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-496C | Mouse Anti-IGFBP7 Recombinant Antibody (clone 20D8) | ELISA | Mouse IgG1, κ |
| VS3-WK50 | Mouse Anti-IGFBP7 Recombinant Antibody (clone E7-D9) | WB, ELISA | Mouse IgG1 |
| VS3-XY848 | Mouse Anti-IGFBP7 Recombinant Antibody (clone 1D9) | ELISA, WB, IHC | Mouse IgG1 |
| VS3-FY741 | Recombinant Rabbit Anti-IGFBP7 Antibody (clone R04-5D9) | WB, IHC-Fr, IHC-P, ICC, IF | Rabbit IgG |
| VS7-0425-WR121 | Mouse Anti-IGFBP7 Recombinant Antibody (clone 1D9E7) | IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC943 | AbPlus™ Anti-IGFBP7 Magnetic Beads (VS-0724-YC943) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1109 | Anti-IGFBP7 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3449 | Anti-Mouse IGFBP7 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3448 | Anti-Human IGFBP7 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3450 | Anti-Rat IGFBP7 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC158 | Recombinant Anti-IGFBP7 Eliminating Antibody, pH-Sensitive (VS-0625-YC158) | Antigen-Sweeping In Vivo. | Mouse IgG1 kappa |
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