Recombinant Lama glama Anti-IGFBP7 Single Domain Antibody (HPAB-AP909-YC) (CAT#: HPAB-AP909-YC)
The sdAb may selectively bind Insulin-like Growth Factor Binding Protein 7 (IGFBP7), which is strongly upregulated in vessels of glioblastoma tumors undergoing neovascularization.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20668/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20668/if_selected.jpg
Figure 2 IHC staining of human kidney
(Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/ihc_selected.jpg
(Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/ihc_selected.jpg
Figure 3 IHC staining of human pancreas
(Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in islet cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20668/ihc_selected.jpg
(Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in islet cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20668/ihc_selected.jpg
Figure 4 Cerebral cortex
(Neuronal cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_B_7_5.jpg
(Neuronal cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_B_7_5.jpg
Figure 5 Colon
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_3.jpg
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_3.jpg
Figure 6 Liver
(Hepatocytes
Staining: Not detected
Intensity:Weak
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_4.jpg
(Hepatocytes
Staining: Not detected
Intensity:Weak
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_4.jpg
Figure 7 Testis
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_5_6.jpg
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_5_6.jpg
Figure 8 Lymph node
(Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_8.jpg
(Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2196/106599_A_8_8.jpg
Figure 9 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, hTERT-RPE1, RPTEC TERT1, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163453-IGFBP7
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163453-IGFBP7
Specifications
- Host Species
- Lama glama
- Type
- Lama glama VHH
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- HPAB-AP909-YC
- Applications
- Function Assay
- Related Disease
- Glioblastoma tumor
Product Property
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-546-F(E) | Recombinant Anti-human IGFBP7 Antibody Fab Fragment | WB, FACS, FuncS | Fab |
| MHH-546-F(E) | Recombinant Human Anti-human IGFBP7 Antibody Fab Fragment | ELISA, Nert, FuncS | Fab |
| HPAB-0134-CN-F(E) | Mouse Anti-IGFBP7 Recombinant Antibody; Fab Fragment (HPAB-0134-CN-F(E)) | ELISA | Mouse Fab |
| HPAB-0135-CN-F(E) | Mouse Anti-IGFBP7 Recombinant Antibody; Fab Fragment (HPAB-0135-CN-F(E)) | ELISA | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
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