Human Anti-IgG Fc Recombinant Antibody (clone A4) (CAT#: FAMAB-0023JF)
Recombinant monoclonal antibody specially binds to human IgG Fc. This human anti-IgG Fc antibody A4 can be potentially used in detection of rheumatoid arthritis.
Specific Inquiry
ELISA
Figure 1 Antigen-binding activity of antihuman IgG1s measured by ELISA.
The mean O.D. values and standard deviations for the nine human cells in each group are shown.
Kanda, Y., Yamada, T., Mori, K., Okazaki, A., Inoue, M., Kitajimamiyama, K., ... & Satoh, M. (2007). Comparison of biological activity among nonfucosylated therapeutic IgG1 antibodies with three different N-linked Fc oligosaccharides: the high-mannose, hybrid, and complex types. Glycobiology, 17(1), 104-118.
FuncS
Figure 2 ADCC activity of antihuman IgG1s.
Comparable data were obtained when WIL2-S cells were employed as target cells (data not shown).
Kanda, Y., Yamada, T., Mori, K., Okazaki, A., Inoue, M., Kitajimamiyama, K., ... & Satoh, M. (2007). Comparison of biological activity among nonfucosylated therapeutic IgG1 antibodies with three different N-linked Fc oligosaccharides: the high-mannose, hybrid, and complex types. Glycobiology, 17(1), 104-118.
Specifications
- Host Species
- Human
- Type
- Human IgM
- Specificity
- Human IgG Fc
- Species Reactivity
- Human
- Clone
- A4
- Applications
- ELISA, FuncS
- Related Disease
- Rheumatoid arthritis
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The IgG Fc antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Functional Assay.
Target
- Alternative Names
- Immunoglobulin G Fc; Fc; IgG-Fc; Immunoglobulin G Fc fragment; Fc fragment
- Function
- Rheumatoid factor activity
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Recombinant Antibody
Fab Fragment Antibody
scFv Fragment Antibody
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-548 | Recombinant Anti-IgG Fc Antibody | ELISA, WB, Dot, FuncS | IgG |
| MHH-548 | Recombinant Human Anti-IgG Fc Antibody | IF, Neut, FuncS | IgG |
| PABZ-080 | Human Anti-IgG Fc Recombinant Antibody (PABZ-080) | WB, IF, FuncS | Human IgG |
| HPAB-S0071-YC | Human Anti-IgG Fc Recombinant Antibody (clone RF-AN) | ELISA | Human IgM |
| VS-0224-XY85 | Goat Anti-Mouse IgG Fc Recombinant Antibody (VS-0224-XY85) | ELISA | Goat IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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