IgG Fc

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Anti-IgG Fc Products

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    • Target: mouse IgG Fc
    • Linker: CL
    • Drug: MD10 (monomethyl dolastatin 10 )
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    • Target: human IgG Fc
    • Linker: CL
    • Drug: MD10 (monomethyl dolastatin 10 )
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For Research Use Only. Not For Clinical Use.


Background

The crystallizable fragment consists of the carboxyl-terminal portions of two immunoglobulin heavy chains interconnected by disulfide bonds. The Fc fragment contains the carboxyl-terminal portions of the heavy chain constant regions, which are responsible for the effector functions of the immunoglobulins (complement fixation, binding to cell membranes via the FC receptor, and placental transport).
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