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IgG Fc

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Anti-IgG Fc Products

    • Target: mouse IgG Fc
    • Linker: CL
    • Drug: MD10 (monomethyl dolastatin 10 )
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    • Target: human IgG Fc
    • Linker: CL
    • Drug: MD10 (monomethyl dolastatin 10 )
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For Research Use Only. Not For Clinical Use.


Background

The fragment crystallizable (Fc) region of immunoglobulin G (IgG) is the tail region of an antibody that interacts with cell surface receptors and proteins of the complement system. The Fc region plays a key role in activating the immune system. The Fc portion of immunoglobulin G (IgG) is a horseshoe-shaped homodimer, which interacts with various effector proteins, including Fcγ receptors (FcγRs).
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