Recombinant Mouse Anti-IgM Antibody (CB16) (CAT#: FAMAB-0043-CN)

This is a mouse monoclonal antibody which specifically reacts with nurse shark IgM. The mAb CB16 recognizes both the 19S and 7S forms of IgM.


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IP

Figure 1 IgM1gj immunoprecipitated from neonatal plasma, neonatal spleen and epigonal organ, and adult epigonal organ has a structure similar to mammalian IgG.

Figure 1 IgM1gj immunoprecipitated from neonatal plasma, neonatal spleen and epigonal organ, and adult epigonal organ has a structure similar to mammalian IgG.

Radio-iodinated IgM1gj in plasma exists as monomers (lower IgM1gj band in lane 3) and dimers (upper IgM1gj band in lane 3) in nonreduced 5% PAGE. Under reducing conditions in 9% PAGE, the H1gj Mr is ≈55 kDa, associated covalently with an L chain. The 80-kDa H chain is derived from 19S and 7S IgM. Lanes 1, NK11 mAb (negative control), lanes 2, CB16 mAb (IgM-specific but noncrossreactive on IgM1gj), lanes 3, GA15 (IgM-specific and crossreactive on IgM1gj).

Rumfelt, L. L., Avila, D., Diaz, M., Bartl, S., McKinney, E. C., & Flajnik, M. F. (2001). A shark antibody heavy chain encoded by a nonsomatically rearranged VDJ is preferentially expressed in early development and is convergent with mammalian IgG. Proceedings of the National Academy of Sciences, 98(4), 1775-1780.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Shark IgM
  • Species Reactivity
  • Nurse shark
  • Clone
  • CB16
  • Applications
  • IP

Product Property

  • Storage
  • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Immunoprecipitation.

Target

  • Alternative Names
  • IgM

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Single-domain Antibody

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NAB-2642-VHH Recombinant Anti-human IgM VHH Single Domain Antibody IHC, ICC, IP, ChiP, Neut Llama VHH
NABG-116 Llama Anti-human IgM VHH Single Domain Antibody [Biotin] ELISA, WB, BLI, SPR

Immunotoxin

CAT Product Name Application Type
AGTO-L025R anti-IGM immunotoxin M6 (IgG)-RTA Cytotoxicity assay, Functional assay

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0269MZ Chicken Anti-Human IgM Polyclonal IgY WB Chicken antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-373CQ Mouse Anti-IgM Recombinant Antibody (clone M15/8) ELISA, FC, IHC-Fr, IP, Block Mouse IgG1, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1778 Rabbit Anti-IgM Recombinant Antibody (clone DS1778AB) ICC, IHC, FC, ELISA Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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