The mAb LK45 is a mouse monoclonal antibody which specifically reacts with nurse shark IgM. This antibody recognizes both the 19S and 7S forms of IgM.
Figure 1 IgM1gj immunoprecipitated from neonatal plasma, neonatal spleen and epigonal organ, and adult epigonal organ has a structure similar to mammalian IgG.
Adult epigonal organ and spleen cells were metabolically labeled with 35S met/cys, and secreted IgM1gj was immunoprecipitated and run in 9% reducing PAGE. Relative to IgM, IgM1gj is maintained at high levels in the epigonal organ. The LK45 mAb I do not cross-react.
Rumfelt, L. L., Avila, D., Diaz, M., Bartl, S., McKinney, E. C., & Flajnik, M. F. (2001). A shark antibody heavy chain encoded by a nonsomatically rearranged VDJ is preferentially expressed in early development and is convergent with mammalian IgG. Proceedings of the National Academy of Sciences, 98(4), 1775-1780.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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MOB-076LC | Mouse Anti-IgM Recombinant Antibody (clone 12M) | ELISA | Mouse IgG |
FAMAB-0134-CN | Mouse Anti-IgM Recombinant Antibody (clone DA4.4) | ELISA | Mouse IgG1, κ |
FAMAB-0135-CN | Rat Anti-IgM Recombinant Antibody (clone Bet2) | ELISA | Rat IgG1, κ |
HPAB-1289WJ | Human Anti-IgM Recombinant Antibody (clone CB2IE12) | ELISA, WB, IF | Human IgG |
HPAB-1290WJ | Human Anti-IgM Recombinant Antibody (clone CB2IE7) | IF, ELISA | Human IgG |
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FAMAB-0031-CN-S(P) | Mouse Anti-IgM Recombinant Antibody (clone 9E1); scFv Fragment | IP, IF | Mouse scFv |
FAMAB-0036-CN-S(P) | Recombinant Mouse Anti-IgM Antibody scFv Fragment (1.14 ) | WB, IP, FC | Mouse scFv |
FAMAB-0042-CN-S(P) | Recombinant Mouse Anti-IgM Antibody scFv Fragment (CB5) | IP | Mouse scFv |
FAMAB-0134-CN-S(P) | Mouse Anti-IgM Recombinant Antibody (clone DA4.4); scFv Fragment | ELISA | Mouse scFv |
FAMAB-0135-CN-S(P) | Rat Anti-IgM Recombinant Antibody (clone Bet2); scFv Fragment | ELISA | Rat scFv |
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FAMAB-0134-CN-F(E) | Mouse Anti-IgM Recombinant Antibody (clone DA4.4); Fab Fragment | ELISA | Mouse Fab |
FAMAB-0135-CN-F(E) | Rat Anti-IgM Recombinant Antibody (clone Bet2); Fab Fragment | ELISA | Rat Fab |
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HPAB-1287WJ-F(E) | Human Anti-IgM Recombinant Antibody (clone CB2bG8); Fab Fragment | ELISA, WB | Human Fab |
HPAB-1288WJ-F(E) | Human Anti-IgM Recombinant Antibody (clone AKJR4); Fab Fragment | ELISA, WB | Human Fab |
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