Human Anti-IL24 Recombinant Antibody (clone 1C10) (CAT#: HPAB-1466LY)

This product is an antibody that recognizes IL-24. The antibody 1C10 can be used for immunoassay techniques such as: ELISA, FC, Blocking.


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  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
IHC

Figure 1 Interleukin (IL)-24-expressing cells in biopsies from patients with ulcerative colitis or Crohn’s disease.

Figure 1 Interleukin (IL)-24-expressing cells in biopsies from patients with ulcerative colitis or Crohn’s disease.

Results are expressed as mean ± standard deviation (s.d.).

Fonseca‐Camarillo, G., Furuzawa‐Carballeda, J., Granados, J., & Yamamoto‐Furusho, J. K. (2014). Expression of interleukin (IL)‐19 and IL‐24 in inflammatory bowel disease patients: a cross‐sectional study. Clinical & Experimental Immunology, 177(1), 64-75.

ELISA

Figure 2 Detection of exogenous IL-24 in mouse serum after electroporation.

Figure 2 Detection of exogenous IL-24 in mouse serum after electroporation.

The absorbance at OD490 nm was measured.

Chen, W. Y., Cheng, Y. T., Lei, H. Y., Chang, C. P., Wang, C. W., & Chang, M. S. (2005). IL-24 inhibits the growth of hepatoma cells in vivo. Genes & Immunity, 6(6), 493-499.

FC

Figure 3 IL-24 expression was quantified by intracellular flow cytometry.

Figure 3 IL-24 expression was quantified by intracellular flow cytometry.

Cytokines induce the expression of IL-24 in keratinocytes.

Poindexter, N. J., Williams, R. R., Powis, G., Jen, E., Caudle, A. S., Chada, S., & Grimm, E. A. (2010). IL‐24 is expressed during wound repair and inhibits TGFα‐induced migration and proliferation of keratinocytes. Experimental dermatology, 19(8), 714-722.

WB

Figure 4 IL-24 inhibition of TGFa-induced proliferation through EGFR.

Figure 4 IL-24 inhibition of TGFa-induced proliferation through EGFR.

Shown are the results of one experiment.

Poindexter, N. J., Williams, R. R., Powis, G., Jen, E., Caudle, A. S., Chada, S., & Grimm, E. A. (2010). IL‐24 is expressed during wound repair and inhibits TGFα‐induced migration and proliferation of keratinocytes. Experimental dermatology, 19(8), 714-722.


Specifications

  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • Human IgG
  • Specificity
  • Human IL24
  • Species Reactivity
  • Human
  • Clone
  • 1C10
  • Applications
  • WB, ELISA, FC, IHC

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The IL24 antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry, Flow Cytometry.

Target

  • Alternative Names
  • C49A; FISP; MDA7; MOB5; ST16; IL10B

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 1C10"

See other products for "IL24"

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1804 Rabbit Anti-IL24 Recombinant Antibody (clone DS1804AB) WB, FC, IP Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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