Human Anti-IL31RA Recombinant Antibody; Fab Fragment (HPAB-J0137-YC-F(E)) (CAT#: HPAB-J0137-YC-F(E))
It is a recombinant human antibody Fab fragment that recognizes IL31RA. The antibody was purified by affinity chromatography. This antibody has potent affinity against mouse IL31RA. It has been determined using Enzyme-linked immunosorbent assay, Inhibition assay and other applications.
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51532/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51532/if_selected.jpg
Figure 2 IHC staining of human lung
(Immunohistochemical staining of human lung shows moderate cytoplasmic positivity in macrophages.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68114/160946_A_3_4_selected.jpg
(Immunohistochemical staining of human lung shows moderate cytoplasmic positivity in macrophages.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68114/160946_A_3_4_selected.jpg
Figure 3 IF staining of human cell line PC-3
(Immunofluorescent staining of human cell line PC-3 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51532/986_C6_2_red_green.jpg
(Immunofluorescent staining of human cell line PC-3 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51532/986_C6_2_red_green.jpg
Figure 4 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51532/832_C6_4_red_green.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51532/832_C6_4_red_green.jpg
Figure 5 Lymph node
(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68114/160946_A_9_8.jpg
(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68114/160946_A_9_8.jpg
Figure 6 RNA cell line category: Cell line enhanced (GAMG, HBEC3-KT, HHSteC, hTERT-HME1, U-2 OS, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164509-IL31RA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164509-IL31RA
Specifications
- Immunogen
- The DNA cartridge prepared with the hNR10 expression vector and the DNA cartridge prepared with the cynNR10 expression vector
- Host Species
- Human
- Derivation
- Humanized (mouse/human)
- Type
- Humanized Fab
- Specificity
- Human IL31RA
- Species Reactivity
- Human
- Applications
- ELISA, Inhib
- Related Disease
- Inflammatory diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- See the COA
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Humanized Antibody Products
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Fab Antibody Products
ScFv-Fc Chimera Products
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-439CQ | Anti-Human IL31RA Recombinant Antibody (TAB-439CQ) | ELISA, IHC, FC, IP, IF, FuncS | IgG2, κ |
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