Mouse Anti-IL31RA Recombinant Antibody; Fab Fragment (HPAB-J0131-YC-F(E)) (CAT#: HPAB-J0131-YC-F(E))
This is a recombinant antibody Fab fragment specific for human IL31RA (Interleukin-31 receptor subunit alpha), derived from mouse. The antibody was purified by affinity chromatography. This antibody suppresses the IL-31-induced IL-6 production in the DU145 cell line in a concentration-dependent manner and thus demonstrates that the antibody has a neutralizing activity against the human IL-31 signaling.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51532/if_selected.jpg

(Immunohistochemical staining of human lung shows moderate cytoplasmic positivity in macrophages.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68114/160946_A_3_4_selected.jpg

(Immunofluorescent staining of human cell line PC-3 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51532/986_C6_2_red_green.jpg

(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51532/832_C6_4_red_green.jpg

(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68114/160946_A_9_8.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164509-IL31RA
Specifications
- Immunogen
- The DNA cartridge prepared with the hNR10 expression vector and the DNA cartridge prepared with the cynNR10 expression vector
- Host Species
- Mouse
- Type
- Mouse Fab
- Specificity
- Human IL31RA
- Species Reactivity
- Human
- Applications
- ELISA, Inhib
- Related Disease
- Inflammatory diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- See the COA
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "IL31RA"
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-439CQ | Anti-Human IL31RA Recombinant Antibody (TAB-439CQ) | ELISA, IHC, FC, IP, IF, FuncS | IgG2, κ |
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