Afuco™ Anti-ITGA4 and ITGB7 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H75) (CAT#: AFC-TAB-H75)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant Humanized (from mouse) antibody to Human ITGA4+ITGB7. It is a monoclonal antibody for the treatment of ulcerative colitis and Crohn's disease.It binds to integrin α4β7 (LPAM-1, lymphocyte Peyer's patch adhesion molecule 1). Blocking the α4β7 integrin results in gut-selective anti-inflammatory activity. It is marketed under the trade name .
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Specificity
- ITGA4_ITGB7(integrin alpha4 (CD49d)_beta7, integrin alpha4_beta7, integrin α4β7, lymphocyte Peyer s patch adhesion molecule 1, LPAM-1) [Homo sapiens]
- Species Reactivity
- Human
- Applications
- FC, IP, ELISA, Neut, FuncS, IF
- Conjugate
- Unconjugated
- Trade name
- Vedolizumab
- Generic Name
- Vedolizumab
- Related Disease
- Ulcerative colitis (UC)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- ITGA4; ITGB7; Integrin α4β7; CD49d/β7
Related Resources
Please refer to Vedolizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Vedolizumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Vedolizumab"
DrugMonitor™ Anti-Vedolizumab Antibody (VS-1224-YC1284)Vedolizumab is an integrin blocker and anti-inflammatory agent used to manage ulcerative colitis and Crohn's disease in adults. The DrugMonitor™ Anti-Vedolizumab Antibody (VS-1224-YC1284) is an anti-drug antibody (ADA) against Vedolizumab. This drug-based antibody is raised in mice immunized with the Vedolizumab. The anti-Vedolizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Vedolizumab in samples.
See other products for "ITGA4 and ITGB7"
Select a product category from the dropdown menu below to view related products.
Please select product type
Human Antibody Products
Humanized Antibody Products
ADCC Enhanced Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H02 | Anti-Human ITGA4+ITGB7 Recombinant Antibody (TAB-H02) | IP, IF, FuncS, FC, Neut, ELISA, WB | IgG2 - kappa |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for AFC-TAB-H75. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
-2.png)
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: ELISA, WB, BLI, SPR
Application: FC, FRET, Internalization
Application: WB, ELISA, IF, FuncS, Apop, BA
Application: Neut, ELISA, FuncS
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, WB, Microarray, Block
-3.jpg)
Application: IB, FC, ELISA, FuncS
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
