Mouse Anti-LDL Recombinant Antibody (clone 1H11) (CAT#: FAMAB-0185JF)
Recombinant monoclonal antibody specially binds to low density lipoprotein (LDL). This mouse anti-LDL antibody (1H11) can be potencially used in the development of vaccines against West Nile Virus.
Specific Inquiry
ELISA
Figure 1 Anti-OxLDL monoclonal antibodies 1H11 distinguish between human OxLDL and native LDL.
Data are expressed as mean optical density ± standard error oftriplicates.
Boyd, H. C., Gown, A. M., Wolfbauer, G., & Chait, A. (1989). Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit. The American journal of pathology, 135(5), 815.
WB
Figure 2 Western blot of human native LDL and OxLDL with antibodies to LDL and to OxLDL.
Prestained molecular weight markers, with molecular weights in kilodaltons at left.
Boyd, H. C., Gown, A. M., Wolfbauer, G., & Chait, A. (1989). Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit. The American journal of pathology, 135(5), 815.
IF
Figure 3 Immunofluorescent detection of LDL in atherosclerotic lesions.
Original magnification X215.
Boyd, H. C., Gown, A. M., Wolfbauer, G., & Chait, A. (1989). Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit. The American journal of pathology, 135(5), 815.
IHC
Figure 4 Demonstration of neoepitope recognition by mAbs by immunohistochemistry.
Scale bars indicate 50 μm.
Torzewski, M., Klouche, M., Hock, J., Meßner, M., Dorweiler, B., Torzewski, J., ... & Bhakdi, S. (1998). Immunohistochemical demonstration of enzymatically modified human LDL and its colocalization with the terminal complement complex in the early atherosclerotic lesion. Arteriosclerosis, thrombosis, and vascular biology, 18(3), 369-378.
Specifications
- Immunogen
- MDA-modified LDL
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human LDL
- Species Reactivity
- Human
- Clone
- 1H11
- Applications
- WB, ELISA, IHC, IF
- Related Disease
- Atherosclerosis
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The LDL antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry, Immunofluorescence.
Target
- Alternative Names
- Low-density lipoprotein; LDL; Ldl cholesterol
Related Resources
Cushing Syndrome
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-615 | Recombinant Anti-LDL Antibody | ELISA, WB, FC, FuncS | IgG |
| MHH-615 | Recombinant Human Anti-LDL Antibody | ELISA, WB, FuncS | IgG |
| MOB-0162MZ | Recombinant Mouse Anti-Human Low Density Lipoprotein Receptor-Related Protein (LRP) (515kDa) Antibody (clone 9H2) | WB, IHC-FoFr, FC | Mouse antibody |
| HPAB-1067WJ | Recombinant Human Anti-LDL Antibody (IEIA8) | ELISA | Human IgG |
| FAMAB-0186JF | Mouse Anti-LDL Recombinant Antibody (clone 4E4) | WB, ELISA, IHC, IF | Mouse IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-615-F(E) | Recombinant Anti-LDL Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
| MHH-615-F(E) | Recombinant Human Anti-LDL Antibody Fab Fragment | RIA, IF, FuncS | Fab |
| HPAB-1067WJ-F(E) | Recombinant Human Anti-LDL Antibody Fab Fragment (IEIA8) | ELISA | Human Fab |
| HPAB-1068WJ-F(E) | Recombinant Human Anti-LDL Antibody Fab Fragment (IEI-E3) | ELISA | Human Fab |
| HPAB-1069WJ-F(E) | Recombinant Human Anti-LDL Antibody Fab Fragment (KTT-D6) | ELISA | Human Fab |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0322MZ | Chicken Anti-LDL Polyclonal IgY | Anti-LDL antibody produced in chicken is suitable for indirect ELISA and WBting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200 | Chicken antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4301 | Hi-Affi™ Recombinant Rabbit Anti-LDL Monoclonal Antibody (SI390DS) | FC | IgG |
| MOR-4302 | Hi-Affi™ Recombinant Rabbit Anti-LDL Monoclonal Antibody (SI391DS) | FC | IgG |
| MOR-4303 | Hi-Affi™ Recombinant Rabbit Anti-LDL Monoclonal Antibody (SI392DS) | FC | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1067WJ-S(P) | Recombinant Human Anti-LDL Antibody scFv Fragment (IEIA8) | ELISA | Human scFv |
| HPAB-1068WJ-S(P) | Recombinant Human Anti-LDL Antibody scFv Fragment (IEI-E3) | ELISA | Human scFv |
| HPAB-1069WJ-S(P) | Recombinant Human Anti-LDL Antibody scFv Fragment (KTT-D6) | ELISA | Human scFv |
| FAMAB-0056JF-S(P) | Human Anti-LDL Recombinant Antibody (clone IK17); scFv Fragment | FACS, WB, IHC, ELISA, FuncS | Human scFv |
| FAMAB-0186JF-S(P) | Mouse Anti-LDL Recombinant Antibody (clone 4E4); scFv Fragment | ICC, WB, ELISA, FuncS | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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