The recombinant monoclonal antibody is specific for acetylated LDL (AcLDL) and malondialdehyde-treated LDL (MDA-LDL). This mouse anti-LDL antibody (4E4) specifically binds to modified LDL present in human atherosclerotic lesions.
Figure 1 Anti-OxLDL monoclonal antibodies 4E4 distinguish between human OxLDL and native LDL.
Data are expressed as mean optical density ± standard error oftriplicates.
Boyd, H. C., Gown, A. M., Wolfbauer, G., & Chait, A. (1989). Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit. The American journal of pathology, 135(5), 815.
Figure 2 Immunofluorescent detection of LDL in atherosclerotic lesions.
Original magnification X175.
Boyd, H. C., Gown, A. M., Wolfbauer, G., & Chait, A. (1989). Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit. The American journal of pathology, 135(5), 815.
Figure 3 Reproduction of a Western blot analysis of the degree of LDL fragmentation and aggregation associated with different times of oxidation.
Reproduction of an agarose gel electrophoretogram of the samples separated by Western blot.
Lopes-Virella, M. F., Koskinen, S., Mironova, M., Horne, D., Klein, R., Chassereau, C., ... & Virella, G. (2000). The preparation of copper-oxidized LDL for the measurement of oxidized LDL antibodies by EIA. Atherosclerosis, 152(1), 107-115.
Figure 4 Immunohistology of the adrenal gland stained with anti-LDL receptor antibody.
High power in zona fasciculata (X200).
Fong, L. G., Bonney, E., Kosek, J. C., & Cooper, A. D. (1989). Immunohistochemical localization of low density lipoprotein receptors in adrenal gland, liver, and intestine. The Journal of clinical investigation, 84(3), 847-856.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-615 | Recombinant Anti-LDL Antibody | ELISA, WB, FC, FuncS | IgG |
MHH-615 | Recombinant Human Anti-LDL Antibody | ELISA, WB, FuncS | IgG |
HPAB-1067WJ | Recombinant Human Anti-LDL Antibody (IEIA8) | ELISA | Human IgG |
HPAB-1068WJ | Recombinant Human Anti-LDL Antibody (IEI-E3) | ELISA | Human IgG |
HPAB-1069WJ | Recombinant Human Anti-LDL Antibody (KTT-D6) | ELISA | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-615-F(E) | Recombinant Anti-LDL Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
MHH-615-F(E) | Recombinant Human Anti-LDL Antibody Fab Fragment | RIA, IF, FuncS | Fab |
HPAB-1067WJ-F(E) | Recombinant Human Anti-LDL Antibody Fab Fragment (IEIA8) | ELISA | Human Fab |
HPAB-1068WJ-F(E) | Recombinant Human Anti-LDL Antibody Fab Fragment (IEI-E3) | ELISA | Human Fab |
FAMAB-0056JF-F(E) | Human Anti-LDL Recombinant Antibody (clone IK17); Fab Fragment | FACS, WB, IHC, ELISA, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-615-S(P) | Recombinant Anti-LDL Antibody scFv Fragment | ELISA, WB, FC, FuncS | scFv |
MHH-615-S(P) | Recombinant Human Anti-LDL Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
FAMAB-0056JF-S(P) | Human Anti-LDL Recombinant Antibody (clone IK17); scFv Fragment | FACS, WB, IHC, ELISA, FuncS | Human scFv |
FAMAB-0185JF-S(P) | Mouse Anti-LDL Recombinant Antibody (clone 1H11); scFv Fragment | ICC, WB, ELISA, FuncS | Mouse scFv |
FAMAB-0186JF-S(P) | Mouse Anti-LDL Recombinant Antibody (clone 4E4); scFv Fragment | ICC, WB, ELISA, FuncS | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0322MZ | Chicken Anti-LDL Polyclonal IgY | Anti-LDL antibody produced in chicken is suitable for indirect ELISA and WBting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200 | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4301 | Hi-Affi™ Recombinant Rabbit Anti-LDL Monoclonal Antibody (SI390DS) | FC | IgG |
MOR-4302 | Hi-Affi™ Recombinant Rabbit Anti-LDL Monoclonal Antibody (SI391DS) | FC | IgG |
MOR-4303 | Hi-Affi™ Recombinant Rabbit Anti-LDL Monoclonal Antibody (SI392DS) | FC | IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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