Mouse Anti-LDLR Recombinant Antibody (clone C7) (CAT#: VS11-QX101)
This product is a recombinant mouse antibody that recognizes ligand binding domain. The antibody binds to the bovine and human LDL-R. However, it does not exhibit cross reactivity with the LDL-Rs of rat, mouse, Chinese hamster, rabbit, and dog. This antibody can be used for the following applications: FC, IP, WB, Inhib, IF.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 IHC staining of human liver
(Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/ihc_selected.jpg
(Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/ihc_selected.jpg
Figure 2 IHC staining of human colon
(Immunohistochemical staining of human colon shows moderate cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13159/29364_A_8_3_selected.jpg
(Immunohistochemical staining of human colon shows moderate cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13159/29364_A_8_3_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranou)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_B_7_5.jpg
(Neuronal cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranou)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_B_7_5.jpg
Figure 4 Stomach
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_A_6_1.jpg
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_A_6_1.jpg
Figure 5 Kidney
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_A_7_5.jpg
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_A_7_5.jpg
Figure 6 Testis
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_A_4_6.jpg
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_A_4_6.jpg
Figure 7 Lymph node
(Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13159/29364_A_9_8.jpg
(Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13159/29364_A_9_8.jpg
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130164-LDLR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130164-LDLR
Specifications
- Immunogen
- The extra cellular domain of the bovine LDL-R
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG2b, κ
- Specificity
- Human and Bovine LDL-R
- Species Reactivity
- Human, Bovine
- Clone
- C7
- Applications
- FC, IP, WB, Inhib, IF
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- 1 mg/mL (Please refer to the vial label for the specific concentration.)
- Buffer
- 0.2 μm filtered solution in PBS
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipped at 4°C.
Target
- Alternative Names
- FH; FHC; FHCL1; LDLCQ2; Low-density lipoprotein receptor
- Gene ID
- 3949
- UniProt ID
- P01130
- Long Name
- Low-density lipoprotein receptor
- Sequence Similarities
- Belongs to the LDLR family.
- Function
- Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Related Resources
Cushing Syndrome
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0029MZ | Recombinant Mouse Anti-Human LDLR Antibody (clone JgG-C8) | WB, FC, IF | Mouse antibody |
| MOB-0040MZ | Recombinant Mouse Anti-Human Lectin-like Oxidized LDL receptor-1 (sLOX-1) Soluble form Antibody (clone C019M) | ELISA | Mouse antibody |
| HPAB-0095-YC | Mouse Anti-LDLR Recombinant Antibody (clone 12G4) | ELISA, WB, IHC, FuncS | Mouse IgG |
| MRO-2011-CN | Rabbit Anti-LDLR Polyclonal Antibody (MRO-2011-CN) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-CJ236 | Rabbit Anti-LDLR Recombinant Antibody (VS3-CJ236) | WB, ICC, IF, IHC, FC | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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