Mouse Anti-LDLR Recombinant Antibody (clone C7) (CAT#: VS11-QX101)
This product is a recombinant mouse antibody that recognizes ligand binding domain. The antibody binds to the bovine and human LDL-R. However, it does not exhibit cross reactivity with the LDL-Rs of rat, mouse, Chinese hamster, rabbit, and dog. This antibody can be used for the following applications: FC, IP, WB, Inhib, IF.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 IHC staining of human liver
(Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/ihc_selected.jpg
(Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/ihc_selected.jpg
Figure 2 IHC staining of human colon
(Immunohistochemical staining of human colon shows moderate cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13159/29364_A_8_3_selected.jpg
(Immunohistochemical staining of human colon shows moderate cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13159/29364_A_8_3_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranou)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_B_7_5.jpg
(Neuronal cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranou)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_B_7_5.jpg
Figure 4 Stomach
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_A_6_1.jpg
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_A_6_1.jpg
Figure 5 Kidney
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_A_7_5.jpg
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_A_7_5.jpg
Figure 6 Testis
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_A_4_6.jpg
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9647/25258_A_4_6.jpg
Figure 7 Lymph node
(Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13159/29364_A_9_8.jpg
(Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13159/29364_A_9_8.jpg
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130164-LDLR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130164-LDLR
Specifications
- Immunogen
- The extra cellular domain of the bovine LDL-R
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG2b, κ
- Specificity
- Human and Bovine LDL-R
- Species Reactivity
- Human, Bovine
- Clone
- C7
- Applications
- FC, IP, WB, Inhib, IF
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- 1 mg/mL (Please refer to the vial label for the specific concentration.)
- Buffer
- 0.2 μm filtered solution in PBS
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipped at 4°C.
Target
- Alternative Names
- FH; FHC; FHCL1; LDLCQ2; Low-density lipoprotein receptor
- Gene ID
- 3949
- UniProt ID
- P01130
- Long Name
- Low-density lipoprotein receptor
- Sequence Similarities
- Belongs to the LDLR family.
- Function
- Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Related Resources
Cushing Syndrome
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0029MZ | Recombinant Mouse Anti-Human LDLR Antibody (clone JgG-C8) | WB, FC, IF | Mouse antibody |
| VS3-CJ236 | Rabbit Anti-LDLR Recombinant Antibody (VS3-CJ236) | WB, ICC, IF, IHC, FC | Rabbit IgG |
| VS3-XY1003 | Mouse Anti-LDLR Recombinant Antibody (clone 1B10H10) | ELISA, WB, IHC, FC | Mouse IgG1 |
| VS3-XY1004 | Mouse Anti-LDLR Recombinant Antibody (clone 7H5B11) | ELISA, WB, FC | Mouse IgG1 |
| VS3-XY1005 | Mouse Anti-LDLR Recombinant Antibody (clone 2D9A12) | ELISA, WB, FC | Mouse IgG1 |
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