Human Anti-LSR Recombinant Antibody (clone S11-01.E02) (CAT#: HPAB-AP137-YC)
The recombinant human monoclonal antibody was generated via phage display screening. This antibody reacts with cyno LSR expressing HEK293 cells and demonstrated CDC activity as measured by flow cytometry.
Specific Inquiry
CDC
Figure 1 shows that anti-LSR human IgG1 antibodies demonstrate CDC activity against HEK293 expressing LSR.
HEK293 cell lines expressing cyno LSR (Cyno LSR Hek) or GFP (GFP MT Hek) were incubated with antibodies against LSR or isotype controls hIgG1 (ET901) or mIgG2a (Mopc173), in the presence of complement, and viability measured after 1 hr to assess % CDC activity.
FC
Figure 2 shows FACS staining of anti-LSR antibodies on HEK293 cells ectopically expressing LSR.
Specifications
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Human LSR
- Species Reactivity
- Human
- Clone
- S11-01.E02
- Applications
- FC, CDC
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The antibody was validated for Flow Cytometry and Complement Dependent Cytotoxicity Assay. For details, refer to Published Data.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1698-sdAb | Recombinant Anti-Human LSR VHH Single Domain Antibody | IP, FC, ChiP, Neut | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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