Recombinant Anti-LSR Vesicular Antibody, EV Displayed (VS-0425-YC651)
CAT#: VS-0425-YC651
The Recombinant Anti-LSR Vesicular Antibody, EV Displayed (VS-0425-YC651) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to LSR-expressed cells or tissues. LSR is involved in processes like skin barrier establishment, located in plasma membrane and tight junctions.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/75309/1833_E6_1_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human stomach
Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7270/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line RT4
Immunofluorescent staining of human cell line RT4 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/75309/1805_E4_1_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 4 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/75309/1893_C12_13_cr5bc43ebeb8447_blue_red_green.jpg
Normal Tissue
Figure 5 Cerebral cortex
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7270/18307_B_7_5.jpg
Normal Tissue
Figure 6 Colon
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7270/18307_A_7_3.jpg
Normal Tissue
Figure 7 Liver
Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7270/18307_A_8_4.jpg
Normal Tissue
Figure 8 Testis
Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7270/18307_A_6_6.jpg
Normal Tissue
Figure 9 Lymph node
Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7270/18307_A_8_8.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (A-431, CACO-2, CAPAN-2, HaCaT, OE19, RT4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000105699-LSR
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- LSR
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Lipolysis stimulated lipoprotein receptor
- Molecular Function
- Receptor
- Cellular Localization
- Plasma membrane, Cell Junctions
- Introduction
- Predicted to be involved in several processes, including establishment of skin barrier; protein localization to tricellular tight junction; and tricellular tight junction assembly. Predicted to act upstream of or within maintenance of blood-brain barrier. Located in plasma membrane and tight junction.
- Alternative Names
- ILDR3, LISCH7
- Gene ID
- 51599
- UniProt ID
- Q86X29
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Downloadable Resources
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
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| TAB-0330CL | Anti-Human LSR Recombinant Antibody (8C8) | FC, WB, BI, ELISA, CDC | Mouse IgG |
| TAB-0330CL-S(P) | Anti-Human LSR Recombinant Antibody scFv Fragment (8C8) | FC, WB, BI, ELISA | |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0058-WJ | Human Anti-LSR Recombinant Antibody (clone S11-04.H07) | ELISA, WB, RIA | Human IgG1 |
| HPAB-AP136-YC | Mouse Anti-LSR Recombinant Antibody (clone 8C8) | FC, CDC | Mouse IgG2a |
| HPAB-AP137-YC | Human Anti-LSR Recombinant Antibody (clone S11-01.E02) | FC, CDC | Human IgG1 |
| HPAB-AP138-YC | Human Anti-LSR Recombinant Antibody (clone S11-01.F08) | FC, CDC | Human IgG1 |
| HPAB-AP139-YC | Human Anti-LSR Recombinant Antibody (clone S11-04.C11) | FC, CDC | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0058-WJ-F(E) | Human Anti-LSR Recombinant Antibody (clone S11-04.H07); Fab Fragment | ELISA, WB, RIA | Human Fab |
| HPAB-AP136-YC-F(E) | Mouse Anti-LSR Recombinant Antibody (clone 8C8); Fab Fragment | FC, CDC | Mouse Fab |
| HPAB-AP137-YC-F(E) | Human Anti-LSR Recombinant Antibody (clone S11-01.E02); Fab Fragment | FC, CDC | Human Fab |
| HPAB-AP138-YC-F(E) | Human Anti-LSR Recombinant Antibody (clone S11-01.F08); Fab Fragment | FC, CDC | Human Fab |
| HPAB-AP139-YC-F(E) | Human Anti-LSR Recombinant Antibody (clone S11-04.C11); Fab Fragment | FC, CDC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP136-YC-S(P) | Mouse Anti-LSR Recombinant Antibody (clone 8C8); scFv Fragment | FC, CDC | Mouse scFv |
| HPAB-AP137-YC-S(P) | Human Anti-LSR Recombinant Antibody (clone S11-01.E02); scFv Fragment | FC, CDC | Human scFv |
| HPAB-AP138-YC-S(P) | Human Anti-LSR Recombinant Antibody (clone S11-01.F08); scFv Fragment | FC, CDC | Human scFv |
| HPAB-AP139-YC-S(P) | Human Anti-LSR Recombinant Antibody (clone S11-04.C11); scFv Fragment | FC, CDC | Human scFv |
| HPAB-AP140-YC-S(P) | Human Anti-LSR Recombinant Antibody (clone S11-04.D11); scFv Fragment | FC, CDC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC136 | Human Anti-LSR Recombinant Antibody Hexamer (VS-0924-YC136), CDC Enhanced | FC, CDC | Antibody hexamer |
| VS-0924-YC137 | Mouse Anti-LSR Recombinant Antibody Hexamer (VS-0924-YC137), CDC Enhanced | FC, WB, BI, ELISA, CDC | Antibody hexamer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4115 | Anti-LSR Immunohistochemistry Kit | IHC |
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